Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5643407 | 0.87 | RIPK1 (0.56) | RIPK1MEN1KMT2AATMNSD2 | |
| SCHEMBL5644735 | 0.86 | RIPK1 (0.54) | RIPK1MEN1KMT2AATMNSD2 | |
| SCHEMBL5644587 | 0.86 | RIPK1 (0.54) | RIPK1MEN1KMT2AATMNSD2 | |
| SCHEMBL5647030 | 0.86 | KMT2A (0.58) | RIPK1MEN1KMT2AATMNSD2 | |
| SCHEMBL5646698 | 0.80 | NSD2 (0.68) | RIPK1MEN1KMT2ANSD2ALDH1A1 | |
| SCHEMBL5644473 | 0.77 | RIPK1 (0.51) | RIPK1MEN1KMT2AATMALDH1A1 | |
| SCHEMBL5643681 | 0.75 | ERCC1 (0.44) | MEN1KMT2ALIMK2HTT | |
| SCHEMBL5451331 | 0.75 | MAOB (0.44) | RIPK1MEN1KMT2AMAOBALDH1A1 | |
| SCHEMBL5646860 | 0.74 | NSD2 (0.44) | RIPK1MEN1KMT2AATMNSD2 | |
| SCHEMBL3964632 | 0.74 | RIPK1 (0.59) | RIPK1KMT2AMAOBALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241759-B2 | Benzo[1,2,5]thiadiazole compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | disclosed |