Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5644735 | 0.85 | RIPK1 (0.54) | RIPK1KMT2AMEN1ATMALDH1A1 | |
| SCHEMBL5647030 | 0.85 | KMT2A (0.58) | RIPK1KMT2AMEN1ATM | |
| SCHEMBL5642804 | 0.81 | MEN1 (0.50) | KMT2AMEN1ALDH1A1HPGDGAA | |
| SCHEMBL5643407 | 0.79 | RIPK1 (0.56) | RIPK1KMT2AMEN1ATMALDH1A1 | |
| SCHEMBL5643958 | 0.77 | KMT2A (0.49) | KMT2AMEN1ATM | |
| SCHEMBL5646227 | 0.77 | RIPK1 (0.54) | RIPK1KMT2AMEN1ATMALDH1A1 | |
| SCHEMBL5644587 | 0.77 | RIPK1 (0.54) | RIPK1KMT2AMEN1ATMALDH1A1 | |
| SCHEMBL5644480 | 0.75 | KMT2A (0.79) | KMT2AMEN1ATMALDH1A1HPGD | |
| SCHEMBL8238900 | 0.74 | CDK4 (0.51) | KMT2AMEN1ATMALDH1A1HPGD | |
| SCHEMBL3964632 | 0.74 | RIPK1 (0.59) | RIPK1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241759-B2 | Benzo[1,2,5]thiadiazole compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | disclosed |