Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.70 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 5/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1473277 | 0.87 | HTR1A (0.52) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL1473380 | 0.81 | HTR1A (0.45) | HTR1A | |
| SCHEMBL1471527 | 0.78 | HTR1A (0.75) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL1473255 | 0.77 | HTR1A (0.39) | HTR1A | |
| SCHEMBL1471529 | 0.76 | HTR1A (0.64) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL6566542 | 0.75 | HTR1A (0.71) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL7700763 | 0.74 | HTR1A (0.70) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL1473252 | 0.74 | HTR1A (0.59) | HTR1AADRA1DADRA1AADRA1BLMNA | |
| SCHEMBL1471583 | 0.73 | HTR1A (0.35) | HTR1ALMNA | |
| SCHEMBL1470711 | 0.72 | HTR1A (0.58) | HTR1AADRA1DADRA1AADRA1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276610-B2 | Aryl piperidine amides | JANSSEN PHARACEUTICA, NV (BE) | 2007-10-02 | — | — | US | claimed |