Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.75 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566542 | 0.78 | HTR1A (0.71) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL5647829 | 0.78 | HTR1A (0.70) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL7700763 | 0.77 | HTR1A (0.70) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL1471418 | 0.74 | HTR1A (0.41) | HTR1ALMNA | |
| SCHEMBL1471529 | 0.73 | HTR1A (0.64) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL6565663 | 0.73 | HTR1A (0.63) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL7704520 | 0.72 | HTR1A (0.61) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL7703235 | 0.70 | HTR1A (0.60) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL6567496 | 0.70 | HTR1A (0.60) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL7704555 | 0.70 | HTR1A (0.59) | HTR1AADRA1DADRA1AADRA1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915420-B2 | Aryl piperidine amides | JANSSEN PHARMACEUTICA NV (BE) | 2011-03-29 | — | — | US | disclosed |