Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.64 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL1470985 | 0.81 | PRMT6 (0.46) | HTR1APRMT6ADRA1DADRA1AADRA1B | |
| SCHEMBL1473252 | 0.81 | HTR1A (0.59) | HTR1ALMNAMAPTHTTKMT2A | |
| SCHEMBL1470711 | 0.78 | HTR1A (0.58) | HTR1ALMNAMAPTHTTKMT2A | |
| SCHEMBL7700763 | 0.77 | HTR1A (0.70) | HTR1AHTR6LMNAALDH1A1MAPT | |
| SCHEMBL5647829 | 0.76 | HTR1A (0.70) | HTR1AHTR6LMNAADRA1DADRA1A | |
| SCHEMBL6566542 | 0.76 | HTR1A (0.71) | HTR1ALMNAALDH1A1ADRA1DADRA1A | |
| SCHEMBL1471527 | 0.73 | HTR1A (0.75) | HTR1AHTR6LMNAADRA1DADRA1A | |
| SCHEMBL1471422 | 0.72 | PRMT6 (0.53) | PRMT6HTR6ALDH1A1MAPTHTT | |
| SCHEMBL7704520 | 0.71 | HTR1A (0.61) | HTR1AHTR6LMNAADRA1DADRA1A | |
| SCHEMBL6565663 | 0.70 | HTR1A (0.63) | HTR1ALMNAALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915420-B2 | Aryl piperidine amides | JANSSEN PHARMACEUTICA NV (BE) | 2011-03-29 | — | — | US | disclosed |