Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 3/20 | 0.34 |
| ▸ | HPN | P05981 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5648267 | 1.00 | CA2 (0.36) | CA2CA12CA9SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL4664308 | 0.99 | CA2 (0.35) | CA2CA12CA9SLC6A3SLC6A4 | |
| SCHEMBL5651164 | 0.86 | SLC6A4 (0.41) | SLC6A4CTSBBACE1MLYCDPTPN1 | |
| SCHEMBL5651161 | 0.86 | SLC6A4 (0.41) | SLC6A4CTSBBACE1MLYCDPTPN1 | |
| SCHEMBL5648426 | 0.86 | TAS1R3 (0.43) | CA2SLC6A3SLC6A4SLC6A2HSD17B10 | |
| SCHEMBL5648423 | 0.86 | TAS1R3 (0.43) | CA2SLC6A3SLC6A4SLC6A2HSD17B10 | |
| Hydrochloric Acid SCHEMBL4664379 | 0.85 | TAS1R3 (0.42) | CA2SLC6A3SLC6A4SLC6A2HSD17B10 | |
| Hydrochloric Acid SCHEMBL4773400 | 0.85 | SLC6A4 (0.40) | SLC6A4CTSBBACE1MLYCDPTPN1 | |
| Hydrochloric Acid SCHEMBL4664377 | 0.85 | TAS1R3 (0.42) | CA2SLC6A3SLC6A4SLC6A2HSD17B10 | |
| Hydrochloric Acid SCHEMBL4773407 | 0.85 | SLC6A4 (0.40) | SLC6A4CTSBBACE1MLYCDPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7144897-B2 | Hydroxy alkyl amines | Elan Oharmaceuticals, Inc. (US) | 2006-12-05 | — | — | US | claimed |
| US-20030166717-A1 | Hydroxy alkyl amines | FRESKOS JOHN (US) | 2003-09-04 | — | — | US | claimed |
| US-20070299263-A1 | Hydroxy Alkyl Amines | Elan Pharmaceuticals, Inc. and Pharmacia & Upjohn Company | 2007-12-27 | — | — | US | disclosed |
| US-7144897-B2 | Hydroxy alkyl amines | Elan Oharmaceuticals, Inc. (US) | 2006-12-05 | — | — | US | disclosed |
| US-20030166717-A1 | Hydroxy alkyl amines | FRESKOS JOHN (US) | 2003-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166717-A1 | Hydroxy alkyl amines | PSEN1, MAOA, PSEN2 | CA2 4597/4885CA12 4276/4885CA9 3851/4885 |
| US-20070299263-A1 | Hydroxy Alkyl Amines | MAOA, PSEN2, PSEN1 | CA2 4612/4885CA12 4191/4885CA9 3773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.