Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5651062 | 0.90 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTHSD17B10PTPN7 | |
| SCHEMBL5650705 | 0.81 | KMT2A (0.43) | ALDH1A1HPGDMAPTKDM4EKMT2A | |
| SCHEMBL5651076 | 0.80 | BCL2L1 (0.47) | ALDH1A1HPGDMAPTHSD17B10HTT | |
| SCHEMBL5647917 | 0.79 | ALOX5 (0.41) | ALDH1A1HPGDMAPTPOLBKDM4E | |
| SCHEMBL5649654 | 0.79 | ALDH1A1 (0.44) | ALDH1A1HPGDMAPTKDM4EKMT2A | |
| SCHEMBL5652629 | 0.78 | PLK1 (0.41) | ALDH1A1HPGDMAPTHSD17B10HTT | |
| SCHEMBL5651227 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTPOLBKDM4E | |
| SCHEMBL5650136 | 0.76 | MAPT (0.51) | ALDH1A1HPGDMAPTHSD17B10POLB | |
| SCHEMBL5651783 | 0.76 | ADORA2B (0.38) | ALDH1A1HPGDMAPTHSD17B10ALOX15 | |
| SCHEMBL5649437 | 0.76 | HPGD (0.44) | ALDH1A1HPGDMAPTPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176215-B2 | Bicyclic oxopyridine and oxopyrimidine derivatives | CELLTECH R&D LIMITED (GB) | 2007-02-13 | — | — | US | disclosed |
| US-20040254200-A1 | Bicyclic oxopyridine and oxopyrimidine derivatives | UCB PHARMA S.A. (BE) | 2004-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254200-A1 | Bicyclic oxopyridine and oxopyrimidine derivatives | MAPK1, ALK, NAT1 | ALDH1A1 1498/4885HPGD 1929/4885MAPT 3795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.