Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1387324 | 0.92 | HIF1A (0.35) | HIF1AL3MBTL1MAPTPOLBALDH1A1 | |
| SCHEMBL5647665 | 0.90 | KMT2A (0.35) | HIF1AMAPTPOLBALDH1A1KDM4E | |
| SCHEMBL29565402 | 0.84 | ALDH1A1 (0.39) | HIF1AL3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL1388942 | 0.84 | ALDH1A1 (0.39) | HIF1AL3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL1387468 | 0.82 | HIF1A (0.36) | HIF1AALDH1A1KDM4EACHEMEN1 | |
| SCHEMBL5646001 | 0.82 | MAPT (0.36) | HIF1AMAPTPOLBALDH1A1KDM4E | |
| SCHEMBL3926851 | 0.79 | DPP4 (0.36) | HIF1AL3MBTL1MAPTPOLBALDH1A1 | |
| SCHEMBL8816487 | 0.78 | ALDH1A1 (0.38) | HIF1AMAPTPOLBALDH1A1KDM4E | |
| SCHEMBL5644893 | 0.77 | HIF1A (0.35) | HIF1APOLBALDH1A1KDM4EACHE | |
| SCHEMBL2400659 | 0.77 | KDM4E (0.38) | HIF1AL3MBTL1MAPTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166357-B2 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL, INC. (US) | 2007-01-23 | — | — | US | claimed |
| US-20040185268-A1 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL LIMITED (IE) | 2004-09-23 | — | — | US | claimed |
| EP-0710367-B1 | PHOTOCHROMIC SUBSTITUTED NAPHTHOPYRAN COMPOUNDS | PPG IND OHIO INC (US) | 2000-08-30 | — | — | EP | claimed |
| US-7166357-B2 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL, INC. (US) | 2007-01-23 | — | — | US | disclosed |
| US-20040185268-A1 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL LIMITED (IE) | 2004-09-23 | — | — | US | disclosed |
| EP-0710367-B1 | PHOTOCHROMIC SUBSTITUTED NAPHTHOPYRAN COMPOUNDS | PPG IND OHIO INC (US) | 2000-08-30 | — | — | EP | disclosed |
| US-5637262-A | REVERSIBLE PHOTOCHROMIC DYES FOR OPHTHALMIC LENSES | TRANSITIONS OPTICAL, INC. (US) | 1997-06-10 | — | — | US | disclosed |
| EP-0710367-A4 | — | — | 1996-05-15 | — | — | EP | disclosed |
| EP-0710367-A1 | PHOTOCHROMIC SUBSTITUTED NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1996-05-08 | — | — | EP | disclosed |
| US-5466398-A | Photochromic substituted naphthopyran compounds | TRANSITIONS OPTICAL, INC. (US) | 1995-11-14 | — | — | US | disclosed |
| WO-1995000867-A1 | PHOTOCHROMIC SUBSTITUTED NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1995-01-05 | — | — | WO | disclosed |