Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1388942 | 0.89 | ALDH1A1 (0.39) | ALDH1A1HIF1AKDM4EPTPN1KMT2A | |
| SCHEMBL29565402 | 0.89 | ALDH1A1 (0.39) | ALDH1A1HIF1AKDM4EPTPN1KMT2A | |
| SCHEMBL1387324 | 0.86 | HIF1A (0.35) | ALDH1A1HIF1AKDM4EHSD17B10HPGD | |
| SCHEMBL1387201 | 0.86 | POLB (0.40) | ALDH1A1HIF1AKDM4EPTPN1KMT2A | |
| SCHEMBL1334167 | 0.78 | PLA2G2A (0.35) | ALDH1A1HIF1AKDM4EKMT2AHPGD | |
| SCHEMBL5648658 | 0.78 | HIF1A (0.33) | ALDH1A1HIF1AKDM4EKMT2APOLB | |
| SCHEMBL5667048 | 0.75 | MAPT (0.40) | ALDH1A1KDM4EKMT2AHSD17B10HPGD | |
| SCHEMBL13061587 | 0.75 | ALOX5 (0.43) | ALDH1A1KDM4EPTPN1KMT2AHPGD | |
| SCHEMBL1387468 | 0.74 | HIF1A (0.36) | ALDH1A1HIF1AKDM4EKMT2A | |
| SCHEMBL5646001 | 0.74 | MAPT (0.36) | ALDH1A1HIF1AKDM4EKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637262-A | REVERSIBLE PHOTOCHROMIC DYES FOR OPHTHALMIC LENSES | TRANSITIONS OPTICAL, INC. (US) | 1997-06-10 | — | — | US | disclosed |
| EP-0710367-A4 | — | — | 1996-05-15 | — | — | EP | disclosed |
| EP-0710367-A1 | PHOTOCHROMIC SUBSTITUTED NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1996-05-08 | — | — | EP | disclosed |
| US-5466398-A | Photochromic substituted naphthopyran compounds | TRANSITIONS OPTICAL, INC. (US) | 1995-11-14 | — | — | US | disclosed |
| WO-1995000867-A1 | PHOTOCHROMIC SUBSTITUTED NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1995-01-05 | — | — | WO | disclosed |