Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A1 | P60842 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1187814 | 0.98 | CA12 (0.32) | EIF4A1CYP3A4ALDH1A1TSHRCYP2C19 | |
| SCHEMBL3698200 | 0.90 | CA12 (0.33) | ALDH1A1TSHRCYP2C19MEN1KMT2A | |
| SCHEMBL30708909 | 0.90 | CA12 (0.33) | ALDH1A1TSHRCYP2C19MEN1KMT2A | |
| SCHEMBL3147233 | 0.88 | PGR (0.33) | ALDH1A1TSHRCYP2C19MEN1KMT2A | |
| SCHEMBL25844009 | 0.88 | TP53 (0.34) | ALDH1A1TSHRCYP2C19MEN1KMT2A | |
| SCHEMBL9899542 | 0.87 | CYP1A1 (0.41) | CYP3A4ALDH1A1TSHRCYP2C19MEN1 | |
| SCHEMBL25603693 | 0.87 | TP53 (0.31) | ALDH1A1TSHRCYP2C19MEN1KMT2A | |
| SCHEMBL5646011 | 0.87 | ALDH1A1 (0.33) | EIF4A1CYP3A4ALDH1A1TSHRCYP2C19 | |
| SCHEMBL29453311 | 0.87 | MEN1 (0.32) | EIF4A1CYP3A4ALDH1A1TSHRCYP2C19 | |
| SCHEMBL1046559 | 0.87 | MEN1 (0.32) | EIF4A1CYP3A4ALDH1A1TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166357-B2 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL, INC. (US) | 2007-01-23 | — | — | US | claimed |
| US-20040185268-A1 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL LIMITED (IE) | 2004-09-23 | — | — | US | claimed |
| US-20040185268-A1 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL LIMITED (IE) | 2004-09-23 | — | — | US | disclosed |