SCHEMBL564890

SCHEMBL564890

NNc1cc(Cl)ncn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30044827 1.00
Hydrochloric Acid SCHEMBL5574787 0.98 KMT2A (0.47)
SCHEMBL4076540 0.82 L3MBTL1 (0.42)
SCHEMBL374406 0.76
SCHEMBL29382825 0.76
SCHEMBL12590021 0.76 NPC1 (0.49)
SCHEMBL17164052 0.74 NPC1 (0.47)
SCHEMBL31051471 0.73
SCHEMBL39924 0.73
SCHEMBL9970901 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062391-A1 HYDRAZIDE CONTAINING NUCLEAR TRANSPORT MODULATORS AND USES THEREOF KARYOPHARM THERAPEUTICS INC (US) 2026-03-05 US disclosed
EP-4702016-A1 PYRIMIDINE COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS BASF SE (DE) 2026-03-04 EP disclosed
CN-115996639-B Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2025-06-13 CN disclosed
US-12291508-B2 Hydrazide containing nuclear transport modulators and uses thereof Karyopharm Therapeutics Inc. (US) 2025-05-06 US disclosed
EP-4523755-A2 QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS F. Hoffmann-La Roche AG (CH) 2025-03-19 EP disclosed
US-20250059161-A1 COMPOUNDS AND METHODS FOR MODULATING STAT3 VIVIDION THERAPEUTICS, INC. 2025-02-20 US disclosed
WO-2024223373-A1 PYRIMIDINE COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS BASF SE (DE) 2024-10-31 WO disclosed
EP-4360713-B1 QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS HOFFMANN LA ROCHE (CH) 2024-10-30 EP disclosed
WO-2024182693-A1 2-AZASPIRO[3.3]HEPTANE DERIVATIVES AS STAT3 INHIBITORS FOR THE TREATMENT OF CANCER VIVIDION THERAPEUTICS, INC. (US) 2024-09-06 WO disclosed
US-20240279188-A1 HYDRAZIDE CONTAINING NUCLEAR TRANSPORT MODULATORS AND USES THEREOF WILMINGTON SAVINGS FUND SOCIETY, FSB, AS AGENT 2024-08-22 US disclosed
US-5084458-A Bactericides, malaria and antitumor agents SCHAPER KLAUS JUERGEN (DE) 1992-01-28 US disclosed
US-4997835-A Bactericides, malaria, antitumor SCHAPER KLAUS JUERGEN (DE) 1991-03-05 US disclosed
EP-0313630-A1 SUBSTITUTED 2-ACYLPYRIDIN-ALPHA-(N)-HETARYLHYDRAZONES AND MEDICAMENTS CONTAINING SAME. DEUTSCHES AUSSATZIGEN HILFSWER (DE) 1989-05-03 EP disclosed
EP-0121341-B1 TRIAZOLO(4,3-C)PYRIMIDINES AND TRIAZOLO(1,5-C)PYRIMIDINES SUBSTITUTED BY NITROGEN-CONTAINING HETEROCYCLIC RINGS RIKER LABORATORIES, INCORPORATED (US) 1988-11-17 EP disclosed
US-4612375-A Substituted 4-hydrazino-pyrimides as intermediates for triazolo [4,3-c]pyrimidines RIKER LABORATORIES, INC. (US) 1986-09-16 US disclosed
US-4572910-A BRONCHODILATORS RIKER LABORATORIES, INC. (US) 1986-02-25 US disclosed
US-4536579-A BRONCHODILATING AGENTS RIKER LABORATORIES, INC. (US) 1985-08-20 US disclosed
US-4532242-A Bronchodilator agents RIKER LABORATORIES, INC. (US) 1985-07-30 US disclosed
US-4477450-A BRONCHODILATORS RIKER LABORATORIES, INC. (US) 1984-10-16 US disclosed
EP-0121341-A1 Triazolo(4,3-c)pyrimidines and triazolo(1,5-c)pyrimidines substituted by nitrogen-containing heterocyclic rings RIKER LABORATORIES, INCORPORATED (US) 1984-10-10 EP disclosed