Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | CPT1A | P50416 | 2/20 | 0.38 |
| ▸ | SCD | O00767 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5649137 | 1.00 | RIPK1 (0.42) | RIPK1SCD5KDM4ECYP2C19KCNK3 | |
| SCHEMBL6646886 | 0.95 | CPT1A (0.42) | RIPK1SCD5KDM4ECYP2C19CPT1A | |
| SCHEMBL22092373 | 0.89 | KDM4E (0.42) | RIPK1SCD5KDM4ECYP2C19HCRTR1 | |
| SCHEMBL6567735 | 0.89 | KDM4E (0.42) | RIPK1SCD5KDM4ECYP2C19HCRTR1 | |
| SCHEMBL1329027 | 0.81 | HSD11B1 (0.55) | RIPK1SCD5KCNK3CPT1AHSD11B1 | |
| SCHEMBL20742564 | 0.78 | CPT1A (0.36) | RIPK1SCD5CPT1AHCRTR1HCRTR2 | |
| SCHEMBL20742779 | 0.78 | CPT1A (0.36) | RIPK1SCD5CPT1AHCRTR1HCRTR2 | |
| SCHEMBL20742561 | 0.78 | CPT1A (0.36) | RIPK1SCD5CPT1AHCRTR1HCRTR2 | |
| SCHEMBL20742597 | 0.77 | PRCP (0.37) | RIPK1SCD5CPT1APRCP | |
| SCHEMBL20742595 | 0.77 | PRCP (0.37) | RIPK1SCD5CPT1APRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166586-B2 | Sulfonamide lactam inhibitors of FXa and method | BRISTOL MYERS SQUIBB CO. (US) | 2007-01-23 | — | — | US | disclosed |
| US-20040186134-A1 | Sulfonamide lactam inhibitors of FXa and method | O'CONNOR STEPHEN P (US) | 2004-09-23 | — | — | US | disclosed |
| US-6555542-B1 | Factor Xa (FXa); useful as anticoagulants in the treatment of cardiovascular diseases associated with thrombosis | BRISTOL-MYERS SQUIBB COMPANY | 2003-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186134-A1 | Sulfonamide lactam inhibitors of FXa and method | STS, SULT1E1, F8 | RIPK1 1193/4885SCD5 695/4885KDM4E 1972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.