SCHEMBL564984

SCHEMBL564984

Nc1cc(Oc2ccc(O)cc2)ccc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
ESR1 P03372 1/20 0.58
ESR2 Q92731 1/20 0.58
ALDH1A1 P00352 4/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
GAA P10253 2/20 0.57
MAPT P10636 2/20 0.57
KDM4E B2RXH2 1/20 0.57
THRB P10828 1/20 0.57
RECQL P46063 1/20 0.57
BLM P54132 1/20 0.57
MCL1 Q07820 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
NR4A1 P22736 1/20 0.52
LTA4H P09960 5/20 0.50
NR1H2 P55055 1/20 0.50
BAX Q07812 1/20 0.50
PARP10 Q53GL7 1/20 0.47
ALOX15 P16050 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17267881 0.94 ALDH1A1 (0.63) MEN1KMT2AESR1ESR2ALDH1A1
SCHEMBL720128 0.94 ALDH1A1 (0.63) MEN1KMT2AESR1ESR2ALDH1A1
SCHEMBL29464083 0.94 ALDH1A1 (0.63) MEN1KMT2AESR1ESR2ALDH1A1
SCHEMBL29935746 0.91 ALDH1A1 (0.65) MEN1KMT2AESR1ESR2ALDH1A1
SCHEMBL335539 0.91 ALDH1A1 (0.65) MEN1KMT2AESR1ESR2ALDH1A1
SCHEMBL29462465 0.91 ALDH1A1 (0.65) MEN1KMT2AESR1ESR2ALDH1A1
SCHEMBL6853379 0.88 ALDH1A1 (0.57) MEN1KMT2AESR1ESR2ALDH1A1
SCHEMBL564763 0.88 ALDH1A1 (0.58) MEN1KMT2AALDH1A1SMN1; SMN2GAA
SCHEMBL6854479 0.88 NR4A1 (0.58) MEN1KMT2AESR1ESR2ALDH1A1
SCHEMBL565006 0.86 MEN1 (0.55) MEN1KMT2AALDH1A1SMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112334795-A Liquid composition, quantum dot-containing film, optical film, light-emitting display element panel, and light-emitting display device 东京应化工业株式会社 2021-02-05 CN disclosed
CN-107429059-B Energy-sensitive resin composition 东京应化工业株式会社 2020-10-23 CN disclosed
CN-105579907-B Radiation-sensitive composition and pattern production method 东京应化工业株式会社 2019-12-17 CN disclosed
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 MEN1 4479/4885KMT2A 2278/4885ESR1 1065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.