Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ARG1 | P05089 | 1/20 | 0.43 |
| ▸ | ARG2 | P78540 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455516 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AARG1ARG2 | |
| SCHEMBL18428222 | 0.92 | ARG1 (0.44) | ALDH1A1MEN1KMT2AARG1ARG2 | |
| SCHEMBL2670096 | 0.86 | CYP2D6 (0.46) | ALDH1A1TSHRCYP2D6BCHEACHE | |
| SCHEMBL14367739 | 0.86 | CYP2D6 (0.46) | ALDH1A1TSHRCYP2D6BCHEACHE | |
| SCHEMBL2670100 | 0.86 | CYP2D6 (0.46) | ALDH1A1TSHRCYP2D6BCHEACHE | |
| SCHEMBL1282150 | 0.86 | CYP2D6 (0.46) | ALDH1A1TSHRCYP2D6BCHEACHE | |
| SCHEMBL2670728 | 0.83 | KMT2A (0.43) | ALDH1A1KMT2ATSHRKDM4ECYP2D6 | |
| SCHEMBL3259925 | 0.83 | S1PR1 (0.47) | ALDH1A1MEN1KMT2AARG1ARG2 | |
| SCHEMBL4487651 | 0.83 | S1PR1 (0.47) | ALDH1A1MEN1KMT2AARG1ARG2 | |
| SCHEMBL3228487 | 0.83 | S1PR1 (0.47) | ALDH1A1MEN1KMT2AARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070270417-A1 | Antibacterial Agents | GLAXO GROUP LIMITED (GB) | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270417-A1 | Antibacterial Agents | NQO2, NQO1, NDUFV2 | ALDH1A1 2750/4885MEN1 2360/4885KMT2A 4492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.