SCHEMBL565034

SCHEMBL565034

Nc1cccc(Nc2ccccc2)c1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.67
GAA P10253 9/20 0.67
KDM4E B2RXH2 7/20 0.67
ALDH1A1 P00352 7/20 0.67
MEN1 O00255 5/20 0.67
KMT2A Q03164 5/20 0.67
LMNA P02545 3/20 0.67
CYP1A2 P05177 2/20 0.67
CYP2C9 P11712 2/20 0.67
CYP2C19 P33261 2/20 0.67
CYP2D6 P10635 1/20 0.67
TDP1 Q9NUW8 5/20 0.52
RECQL P46063 2/20 0.52
GLA P06280 1/20 0.52
HPGD P15428 4/20 0.52
HSD17B10 Q99714 3/20 0.52
ALOX15 P16050 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
TP53 P04637 2/20 0.52
APP P05067 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL564707 0.85 MMP2 (0.45) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL4372485 0.85 MAPT (0.62) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL217480 0.81 MAPT (1.00) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL29388147 0.81 MAPT (1.00) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL31484215 0.79 MAPT (0.72) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL16934632 0.79 MAPT (0.72) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL27294589 0.79 MAPT (0.56) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL10932219 0.79 KDM4E (0.50) MAPTGAAKDM4EALDH1A1MEN1
Methane SCHEMBL4054340 0.79 MAPT (0.95) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL6576141 0.79 MAPT (0.95) MAPTGAAKDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 MAPT 3886/4885GAA 3993/4885KDM4E 3369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.