Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23001584 | 0.86 | SIGMAR1 (0.52) | SIGMAR1ALDH1A1CHRM2CHRM5CHRM1 | |
| SCHEMBL5493436 | 0.84 | SIGMAR1 (0.51) | SIGMAR1ALDH1A1CHRM2CHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL5493434 | 0.83 | SIGMAR1 (0.50) | SIGMAR1ALDH1A1CHRM2CHRM5CHRM1 | |
| SCHEMBL6172740 | 0.79 | SIGMAR1 (0.49) | SIGMAR1ALDH1A1CHRM2CHRM5CHRM1 | |
| SCHEMBL4283767 | 0.79 | HRH3 (0.56) | SIGMAR1ALDH1A1HRH3 | |
| SCHEMBL25416506 | 0.78 | MEN1 (0.51) | SIGMAR1ALDH1A1OPRK1MEN1KMT2A | |
| SCHEMBL29837200 | 0.77 | SIGMAR1 (0.45) | SIGMAR1ALDH1A1CHRM2CHRM5CHRM1 | |
| SCHEMBL23944892 | 0.77 | ALDH1A1 (0.58) | SIGMAR1ALDH1A1MAPTHPGDKMT2A | |
| Benzyl Dimethylcarbamate SCHEMBL20401678 | 0.77 | ALDH1A1 (0.62) | SIGMAR1ALDH1A1MAPTHPGDKMT2A | |
| Benzyl Dimethylcarbamate SCHEMBL5134244 | 0.77 | ALDH1A1 (0.62) | SIGMAR1ALDH1A1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223776-B2 | Compounds with anti-bacterial activity | MORPHOCHEM AG (DE) | 2007-05-29 | — | — | US | disclosed |
| US-20060040949-A1 | Novel compounds with antibacterial activity | MORPHOCHEM AG | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040949-A1 | Novel compounds with antibacterial activity | MRPL21, Q6ZSR9, MRPL19 | SIGMAR1 882/4885ALDH1A1 2434/4885MAPT 4752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.