Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 3/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5493434 | 0.99 | SIGMAR1 (0.50) | SIGMAR1ALDH1A1CHRM2CHRM1CHRM3 | |
| SCHEMBL5650503 | 0.84 | SIGMAR1 (0.57) | SIGMAR1ALDH1A1CHRM2CHRM1CHRM3 | |
| SCHEMBL23001584 | 0.82 | SIGMAR1 (0.52) | SIGMAR1ALDH1A1CHRM2CHRM1CHRM3 | |
| SCHEMBL5418432 | 0.76 | CTSB (0.58) | MEN1KMT2ARAB9A | |
| SCHEMBL6172740 | 0.76 | SIGMAR1 (0.49) | SIGMAR1ALDH1A1CHRM2CHRM1CHRM3 | |
| SCHEMBL5650944 | 0.75 | ALDH1A1 (0.48) | ALDH1A1FKBP1AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13661596 | 0.75 | SIGMAR1 (0.46) | SIGMAR1ALDH1A1HRH3NPC1RAB9A | |
| SCHEMBL29837200 | 0.74 | SIGMAR1 (0.45) | SIGMAR1ALDH1A1CHRM2CHRM1CHRM3 | |
| SCHEMBL15479668 | 0.74 | ALDH1A1 (0.58) | SIGMAR1ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL16665613 | 0.74 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192973-B2 | Piperidine derivatives and their use as modulators of chemokine receptor activity (especially CCR5) | ASTRAZENECA AB (SE) | 2007-03-20 | — | — | US | disclosed |
| US-20040267016-A1 | Piperidine derivatives and their use as modulators of chemokine receptor activity (especially ccr5) | ASTRAZENECA AB (SE) | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040267016-A1 | Piperidine derivatives and their use as modulators of chemokine receptor activity (especially ccr5) | CCR5, CCR2, CCR1 | SIGMAR1 357/4885ALDH1A1 741/4885CHRM2 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.