Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5072741 | 0.87 | ALDH1A1 (0.42) | SCN9AALDH1A1HTTUSP2NPC1 | |
| SCHEMBL1597242 | 0.87 | SCN9A (0.49) | SCN9AALDH1A1HTTUSP2CCR2 | |
| SCHEMBL6176496 | 0.84 | KMT2A (0.47) | SCN9AALDH1A1 | |
| SCHEMBL6176499 | 0.84 | KMT2A (0.47) | SCN9AALDH1A1 | |
| SCHEMBL8569545 | 0.82 | LTA4H (0.42) | SCN9A | |
| SCHEMBL3234426 | 0.82 | ALDH1A1 (0.43) | ALDH1A1HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6180101 | 0.81 | HPGD (0.51) | SMN1; SMN2 | |
| SCHEMBL6180105 | 0.81 | HPGD (0.51) | SMN1; SMN2 | |
| SCHEMBL310438 | 0.81 | CXCR4 (0.49) | ALDH1A1 | |
| SCHEMBL1190365 | 0.81 | CXCR4 (0.49) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223776-B2 | Compounds with anti-bacterial activity | MORPHOCHEM AG (DE) | 2007-05-29 | — | — | US | disclosed |
| US-20060040949-A1 | Novel compounds with antibacterial activity | MORPHOCHEM AG | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040949-A1 | Novel compounds with antibacterial activity | MRPL21, Q6ZSR9, MRPL19 | SCN9A 1796/4885ALDH1A1 2434/4885HTT 4835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.