Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | HTR3A | P46098 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5653732 | 0.99 | PARP1 (0.47) | PARP1KDM4ELMNAMAPTCA1 | |
| SCHEMBL5652540 | 0.91 | HPGD (0.52) | PARP1KDM4ELMNAMAPTCA1 | |
| SCHEMBL2958735 | 0.86 | MEN1 (0.47) | PARP1KDM4ELMNAMAPTHTR3A | |
| SCHEMBL5651076 | 0.86 | BCL2L1 (0.47) | PARP1KDM4ELMNAMAPTCA1 | |
| SCHEMBL5652071 | 0.85 | HTT (0.51) | KDM4ELMNAMAPTMEN1KMT2A | |
| SCHEMBL5654415 | 0.83 | HIF1A (0.38) | KDM4ELMNAMAPTMEN1KMT2A | |
| SCHEMBL5652095 | 0.82 | HPGD (0.45) | KDM4ELMNAMAPTMEN1KMT2A | |
| SCHEMBL5649437 | 0.81 | HPGD (0.44) | KDM4ELMNAMAPTKMT2APOLB | |
| SCHEMBL2950047 | 0.79 | HTR3A (0.44) | PARP1KDM4EHTR3AMEN1KMT2A | |
| SCHEMBL5652375 | 0.79 | SMN1; SMN2 (0.46) | KDM4ELMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176215-B2 | Bicyclic oxopyridine and oxopyrimidine derivatives | CELLTECH R&D LIMITED (GB) | 2007-02-13 | — | — | US | claimed |
| US-20050059681-A1 | Far field light microscopical method system and computer program product for analysing at least one object having a subwavelength size | RUPRECHT-KARLS-UNIVERSITAT HEIDELBERG (DE) | 2005-03-17 | — | — | US | claimed |
| US-20040254200-A1 | Bicyclic oxopyridine and oxopyrimidine derivatives | UCB PHARMA S.A. (BE) | 2004-12-16 | — | — | US | claimed |
| US-7176215-B2 | Bicyclic oxopyridine and oxopyrimidine derivatives | CELLTECH R&D LIMITED (GB) | 2007-02-13 | — | — | US | disclosed |
| US-20040254200-A1 | Bicyclic oxopyridine and oxopyrimidine derivatives | UCB PHARMA S.A. (BE) | 2004-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059681-A1 | Far field light microscopical method system and computer program product for analysing at least one object having a subwavelength size | CFL1, INF2, COG6 | PARP1 3419/4885KDM4E 4849/4885LMNA 2270/4885 |
| US-20040254200-A1 | Bicyclic oxopyridine and oxopyrimidine derivatives | MAPK1, ALK, NAT1 | PARP1 336/4885KDM4E 3821/4885LMNA 1417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.