Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 1/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | CBFB | Q13951 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5651274 | 0.93 | SORT1 (0.52) | SORT1DGAT1KCNH2MAPTSMN1; SMN2 | |
| SCHEMBL5648735 | 0.82 | NPSR1 (0.43) | SMN1; SMN2ALDH1A1LMNAHTTNAMPT | |
| SCHEMBL5648741 | 0.82 | NPSR1 (0.43) | SMN1; SMN2ALDH1A1LMNAHTTNAMPT | |
| SCHEMBL5653471 | 0.79 | HTT (0.47) | MAPTALDH1A1LMNAHTTSLC40A1 | |
| SCHEMBL5651260 | 0.77 | DGAT1 (0.48) | SORT1DGAT1KCNH2MAPTSMN1; SMN2 | |
| SCHEMBL5648366 | 0.75 | ACKR3 (0.47) | DGAT1KCNH2MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5653423 | 0.75 | TSHR (0.44) | MAPTALDH1A1LMNAHTTNAMPT | |
| SCHEMBL5653421 | 0.75 | TSHR (0.44) | ALDH1A1LMNAHTTNAMPTNPSR1 | |
| SCHEMBL5649026 | 0.73 | DGAT1 (0.43) | DGAT1KCNH2NPBWR1CBFB | |
| SCHEMBL5651069 | 0.73 | MEN1 (0.51) | DGAT1KCNH2MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220769-B2 | Azolylbenzamides and analogues and their use for treating osteoporosis | NIKEM RESEARCH S.R.L. (IT) | 2007-05-22 | — | — | US | disclosed |
| US-20050038095-A1 | Azolylbenzamides and analogues and their use for treating osteoporosis | 3-V BIOSCIENCES, INC. | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038095-A1 | Azolylbenzamides and analogues and their use for treating osteoporosis | NR0B2, NR0B1, NCOR1 | SORT1 4615/4885DGAT1 2386/4885KCNH2 3319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.