SCHEMBL565133

SCHEMBL565133

COc1cc(C=O)cc(Br)c1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.64
KDM4E B2RXH2 4/20 0.64
EGFR P00533 1/20 0.59
ALOX5 P09917 1/20 0.58
PTGS2 P35354 1/20 0.58
ERN1 O75460 3/20 0.57
LCK P06239 3/20 0.55
ALDH1A1 P00352 6/20 0.54
MAPK1 P28482 1/20 0.54
TRIM24 O15164 1/20 0.53
HPGD P15428 1/20 0.53
ALDH5A1 P51649 1/20 0.53
ABAT P80404 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
TRIM33 Q9UPN9 1/20 0.53
GFER P55789 1/20 0.52
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
POLB P06746 1/20 0.51
PTP4A3 O75365 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29361178 1.00 GAA (0.64) GAAKDM4EEGFRALOX5PTGS2
Water SCHEMBL10457877 0.98 GAA (0.62) GAAKDM4EEGFRALOX5PTGS2
SCHEMBL21694048 0.92 ALDH1A1 (0.58) GAAKDM4EEGFRALOX5PTGS2
Glycine SCHEMBL8218338 0.88 GAA (0.59) GAAKDM4EEGFRALOX5PTGS2
Syringaldehyde SCHEMBL30119623 0.86 ALDH1A1 (0.62) GAAKDM4EPTGS2ERN1ALDH1A1
Syringaldehyde SCHEMBL150376 0.86 ALDH1A1 (0.62) GAAKDM4EPTGS2ERN1ALDH1A1
Syringaldehyde SCHEMBL2110596 0.86 ALDH1A1 (0.62) GAAKDM4EPTGS2ERN1ALDH1A1
Syringaldehyde SCHEMBL11013780 0.84 ALDH1A1 (0.60) GAAKDM4EPTGS2ERN1ALDH1A1
Syringaldehyde SCHEMBL29724072 0.84 ALDH1A1 (0.60) GAAKDM4EPTGS2ERN1ALDH1A1
Syringaldehyde SCHEMBL28642631 0.84 ALDH1A1 (0.60) GAAKDM4EPTGS2ERN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 711 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 US claimed
CN-113045578-B Novel total synthesis method of racemized tetrandrine 浙江金华康恩贝生物制药有限公司 2023-05-26 CN claimed
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2023-02-02 US claimed
US-20220257483-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL HENKEL AG & CO. KGAA (DE) 2022-08-18 US claimed
CN-114746069-A Three-step multi-tone hair dyeing method 汉高股份有限及两合公司 2022-07-12 CN claimed
EP-4003286-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL Henkel AG & Co. KGaA (DE) 2022-06-01 EP claimed
CN-114173750-A Improving the stability of agents for treating keratin materials 汉高股份有限及两合公司 2022-03-11 CN claimed
CN-109942593-B Total synthesis method of racemic tetrandrine 浙江金华康恩贝生物制药有限公司 2021-08-27 CN claimed
CN-113045578-A Novel total synthesis method of racemic tetrandrine 浙江金华康恩贝生物制药有限公司 2021-06-29 CN claimed
WO-2021110306-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2021-06-10 WO claimed
EP-0488860-B1 Method for the production of polyalkoxylated aromatic compounds RHONE POULENC CHIMIE (FR) 1995-10-11 EP claimed
EP-0423010-B1 METHOD FOR THE PRODUCTION OF ALKOXYBENZALDEHYDES RHONE-POULENC CHIMIE (FR) 1993-09-29 EP claimed
EP-0277894-B1 PROCESS FOR THE PREPARATION OF TRIALKOXYBENZALDEHYDE RHONE-POULENC CHIMIE (FR) 1992-01-29 EP claimed
US-4933498-A HYDROLYZING BROMO-HYDROXY-METHOXY BENZALDEHYDE, DIRECTLY ETHERIFYING WITH A LOWER ALKYL HALIDE RHONE-POULENC CHIMIE (FR) 1990-06-12 US claimed
US-4551558-A OXIDATION AFTER BROMINATION RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-11-05 US claimed
US-4551557-A Bromination of substituted benzaldehydes RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-11-05 US claimed
US-4473713-A Hydrolysis of aryl-aliphatic ethers RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-09-25 US claimed
US-4380629-A Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1983-04-19 US claimed
US-4218567-A Process for aromatic ethers HOFFMANN-LA ROCHE INC. (US) 1980-08-19 US claimed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220257483-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL KRT18, VIM, CDH1 GAA 1325/4885KDM4E 344/4885EGFR 1703/4885
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO GAA 2405/4885KDM4E 1526/4885EGFR 1786/4885
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS TYR, HAO2, HAAO GAA 2405/4885KDM4E 1526/4885EGFR 1786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.