SCHEMBL565140

SCHEMBL565140

CC(C)(c1ccc(N)cc1)c1ccc(O)c(N)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.66
GAA P10253 3/20 0.66
MEN1 O00255 2/20 0.66
MAPT P10636 2/20 0.66
RECQL P46063 2/20 0.66
KMT2A Q03164 2/20 0.66
PKM P14618 1/20 0.66
ESR1 P03372 5/20 0.53
CHEK1 O14757 1/20 0.49
FYN P06241 1/20 0.49
PDGFRB P09619 1/20 0.49
PIM1 P11309 1/20 0.49
FGFR1 P11362 1/20 0.49
FLT1 P17948 1/20 0.49
GRK5 P34947 1/20 0.49
MAP2K2 P36507 1/20 0.49
MAPK8 P45983 1/20 0.49
CDK8 P49336 1/20 0.49
RPS6KA3 P51812 1/20 0.49
PRKX P51817 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17028798 0.94 ALDH1A1 (0.73) ALDH1A1GAAMEN1MAPTRECQL
SCHEMBL29555588 0.92 ALDH1A1 (0.76) ALDH1A1GAAMEN1MAPTRECQL
SCHEMBL336594 0.92 ALDH1A1 (0.76) ALDH1A1GAAMEN1MAPTRECQL
SCHEMBL29412585 0.92 ALDH1A1 (0.76) ALDH1A1GAAMEN1MAPTRECQL
Hydrochloric Acid SCHEMBL30172192 0.90 ALDH1A1 (0.73) ALDH1A1GAAMEN1MAPTRECQL
SCHEMBL36206771 0.89 ALDH1A1 (0.66) ALDH1A1GAAMEN1MAPTRECQL
SCHEMBL563910 0.89 ALDH1A1 (0.66) ALDH1A1GAAMEN1MAPTRECQL
SCHEMBL14119800 0.87 ALDH1A1 (0.63) ALDH1A1GAAMEN1MAPTRECQL
SCHEMBL565029 0.87 ALDH1A1 (0.63) ALDH1A1GAAMEN1MAPTRECQL
SCHEMBL17038648 0.85 ALDH1A1 (0.66) ALDH1A1GAAMEN1MAPTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 ALDH1A1 204/4885GAA 3993/4885MEN1 4479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.