Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 5/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | TACR2 | P21452 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5739747 | 0.94 | PTGER4 (0.42) | PTGER4SIRT5TAS1R3TAS1R1MCHR1 | |
| SCHEMBL5652891 | 0.91 | PTGER4 (0.48) | PTGER4SIRT5FOLH1TAS1R3TAS1R1 | |
| SCHEMBL5652220 | 0.90 | PTGER4 (0.55) | PTGER4SIRT5FOLH1TAS1R3TAS1R1 | |
| SCHEMBL5654575 | 0.89 | PTGER4 (0.48) | PTGER4SIRT5FOLH1TAS1R3TAS1R1 | |
| SCHEMBL5655940 | 0.88 | PTGER4 (0.47) | PTGER4SIRT5TAS1R3TAS1R1MCHR1 | |
| SCHEMBL5654934 | 0.88 | PTGER4 (0.48) | PTGER4SIRT5TAS1R3TAS1R1HDAC3 | |
| SCHEMBL5652300 | 0.84 | PIN1 (0.42) | PTGER4SIRT5TAS1R3TAS1R1MCHR1 | |
| SCHEMBL5652835 | 0.84 | PTGER4 (0.47) | PTGER4SIRT5TAS1R3TAS1R1HDAC3 | |
| SCHEMBL5653677 | 0.83 | TAS1R3 (0.43) | PTGER4TAS1R3TAS1R1MCHR1HDAC3 | |
| SCHEMBL5654371 | 0.83 | TAS1R3 (0.42) | PTGER4TAS1R3TAS1R1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142638-A1 | Ornithine derivatives as prostaglandin e2 agonists or antagonists | ASTELLAS PHARMA INC. (JP) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142638-A1 | Ornithine derivatives as prostaglandin e2 agonists or antagonists | PTGER4, OXER1, RXFP4 | PTGER4 1/4885SIRT5 1504/4885FOLH1 2951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.