Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 4/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5655940 | 0.93 | PTGER4 (0.47) | TAS1R3TAS1R1PTGER4RAB9ACTSK | |
| SCHEMBL5654371 | 0.92 | TAS1R3 (0.42) | TAS1R3TAS1R1PTGER4RAB9ACTSK | |
| SCHEMBL5654934 | 0.92 | PTGER4 (0.48) | TAS1R3TAS1R1PTGER4HDAC3HDAC4 | |
| SCHEMBL5652300 | 0.90 | PIN1 (0.42) | TAS1R3TAS1R1PTGER4RAB9AMCHR1 | |
| SCHEMBL5739747 | 0.90 | PTGER4 (0.42) | TAS1R3TAS1R1PTGER4RAB9ACTSK | |
| SCHEMBL5654500 | 0.89 | TAS1R3 (0.41) | TAS1R3TAS1R1PTGER4RAB9AMCHR1 | |
| SCHEMBL5652835 | 0.84 | PTGER4 (0.47) | TAS1R3TAS1R1PTGER4BCHEACHE | |
| SCHEMBL5654575 | 0.84 | PTGER4 (0.48) | TAS1R3TAS1R1PTGER4PIN1HDAC1 | |
| SCHEMBL5655216 | 0.83 | HDAC1 (0.40) | PTGER4CTSSHDAC3HDAC1HDAC2 | |
| SCHEMBL5651559 | 0.83 | PTGER4 (0.47) | TAS1R3TAS1R1PTGER4MCHR1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142638-A1 | Ornithine derivatives as prostaglandin e2 agonists or antagonists | ASTELLAS PHARMA INC. (JP) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142638-A1 | Ornithine derivatives as prostaglandin e2 agonists or antagonists | PTGER4, OXER1, RXFP4 | TAS1R3 2373/4885TAS1R1 2391/4885PTGER4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.