Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5651787 | 0.88 | ALDH1A1 (0.47) | ALDH1A1HPGDKMT2ALMNAGAA | |
| SCHEMBL5650136 | 0.86 | MAPT (0.51) | ALDH1A1HPGDKMT2ALMNAGAA | |
| SCHEMBL5654426 | 0.86 | ALDH1A1 (0.50) | ALDH1A1HPGDKMT2ALMNAGAA | |
| SCHEMBL5652446 | 0.85 | ALDH1A1 (0.38) | ALDH1A1HPGDKMT2ALMNAGAA | |
| SCHEMBL5651272 | 0.85 | MAPK14 (0.39) | ALDH1A1HPGDKMT2ALMNAGAA | |
| SCHEMBL5651917 | 0.84 | ALDH1A1 (0.41) | ALDH1A1HPGDKMT2AGAAGRM6 | |
| SCHEMBL5648531 | 0.84 | ALDH1A1 (0.47) | ALDH1A1HPGDKMT2AGAAMAPK1 | |
| SCHEMBL5650867 | 0.83 | MAPT (0.47) | ALDH1A1HPGDKMT2ALMNAGAA | |
| SCHEMBL5652595 | 0.82 | MAPT (0.45) | ALDH1A1HPGDKMT2ALMNAGAA | |
| SCHEMBL5652764 | 0.82 | MAPT (0.45) | ALDH1A1HPGDKMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176215-B2 | Bicyclic oxopyridine and oxopyrimidine derivatives | CELLTECH R&D LIMITED (GB) | 2007-02-13 | — | — | US | claimed |
| US-20050059681-A1 | Far field light microscopical method system and computer program product for analysing at least one object having a subwavelength size | RUPRECHT-KARLS-UNIVERSITAT HEIDELBERG (DE) | 2005-03-17 | — | — | US | claimed |
| US-20040254200-A1 | Bicyclic oxopyridine and oxopyrimidine derivatives | UCB PHARMA S.A. (BE) | 2004-12-16 | — | — | US | claimed |
| US-7176215-B2 | Bicyclic oxopyridine and oxopyrimidine derivatives | CELLTECH R&D LIMITED (GB) | 2007-02-13 | — | — | US | disclosed |
| US-20040254200-A1 | Bicyclic oxopyridine and oxopyrimidine derivatives | UCB PHARMA S.A. (BE) | 2004-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059681-A1 | Far field light microscopical method system and computer program product for analysing at least one object having a subwavelength size | CFL1, INF2, COG6 | ALDH1A1 2400/4885HPGD 3158/4885KMT2A 3813/4885 |
| US-20040254200-A1 | Bicyclic oxopyridine and oxopyrimidine derivatives | MAPK1, ALK, NAT1 | ALDH1A1 1498/4885HPGD 1929/4885KMT2A 1815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.