SCHEMBL8528700

SCHEMBL8528700

O=C(O)c1[c]cc2[c]cccc2c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 2/20 0.33
KDM4E B2RXH2 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ALDH1A1 P00352 2/20 0.32
TSHR P16473 2/20 0.32
HPGD P15428 2/20 0.32
HSD17B10 Q99714 2/20 0.32
CYP1A2 P05177 1/20 0.32
GLA P06280 1/20 0.32
CYP2C19 P33261 1/20 0.32
ALOX15 P16050 1/20 0.32
ACMSD Q8TDX5 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CCR2 P41597 1/20 0.32
MCL1 Q07820 1/20 0.32
MGAM O43451 1/20 0.31
IDO1 P14902 1/20 0.31
MAPT P10636 1/20 0.30
SRD5A2 P31213 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3899987 0.77 IDO1 (0.42) DAOKDM4EMEN1KMT2AALDH1A1
SCHEMBL3911957 0.74 KDM4E (0.42) DAOKDM4EMEN1KMT2AALDH1A1
SCHEMBL9776324 0.74 IDO1 (0.44) KDM4EMEN1KMT2AALDH1A1TSHR
SCHEMBL5652182 0.73 PTPN1 (0.47) KDM4EMEN1KMT2AALDH1A1TSHR
SCHEMBL10863575 0.71 CCR2 (0.35) DAOKDM4EMEN1KMT2AALDH1A1
SCHEMBL6633670 0.69 MEN1 (0.44) KDM4EMEN1KMT2AALDH1A1TSHR
SCHEMBL756551 0.69 CYP2A6 (0.32)
SCHEMBL19047861 0.68 KDM4E (0.39) DAOKDM4EMEN1KMT2AALDH1A1
SCHEMBL1921671 0.67 ALDH1A1 (0.32) ALDH1A1HPGDGLAMAPT
SCHEMBL3906521 0.66 IDO1 (0.34) KDM4EMEN1KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0474227-B2 Functionalized peroxides for polymerization reactions ATOCHEM NORTH AMERICA ELF (US) 1998-06-10 EP disclosed
US-5723562-A BLOCK, GRAFT, AND CONDENSATION POLYMERIZATION; ESTERIFICATION, AMIDATION, ETHERIFICATION, CARBAMYLATION ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-03-03 US disclosed
US-5710213-A POLYMERIZING AN UNSATURATED MONOMER OR GRAFTING AN UNSATURATED POLYMER ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-01-20 US disclosed
US-5710210-A Process for polymer reactions with functionalized peroxides ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-01-20 US disclosed
US-5612439-A REACTING WITH MONOMERS TO FORM POLYCARBONATES, POLYESTERS, POLYAMIDES, POLYUREAS, POLYIMIDES, POLYETHERS, AND POLYURETHANES; CURING, CROSSLINKING ELF ATOCHEM NORTH AMERICA, INC. (US) 1997-03-18 US disclosed
US-5543553-A CROSSLINKING, GRAFTING AND CURING AGENTS FOR CONDENSATIONPOLYMERS ELF ATOCHEM NORTH AMERICA, INC. (US) 1996-08-06 US disclosed
US-5536790-A MOLECULAR WEIGHT CONTROL FOR POLYMERS USING PEROXY COMPOUNDS ELF ATOCHEM NORTH AMERICA, INC. (US) 1996-07-16 US disclosed
US-5534596-A CATALYSTS FOR ADDITION POLYMERIZATION, GRAFT POLYMERIZATION, CURING OF UNSATURATED POLYESTERS ELF ATOCHEM NORTH AMERICA, INC. (US) 1996-07-09 US disclosed
US-5466855-A Functionalized peroxides for polymerization reactions ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-11-14 US disclosed
US-5319130-A Monomers for condensation polymers; polyepoxides; addition polymerization initiators; compatibilizers of blends ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-06-07 US disclosed
EP-0474227-A1 Functionalized peroxides for polymerization reactions ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-03-11 EP disclosed