Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815751 | 0.85 | ERN1 (0.58) | ALDH1A1SMN1; SMN2KMT2AMAPTRAB9A | |
| SCHEMBL28433847 | 0.84 | KMT2A (0.46) | ALDH1A1SMN1; SMN2KMT2AMAPTRAB9A | |
| SCHEMBL17461847 | 0.84 | ALDH1A1 (0.52) | ALDH1A1GAASMN1; SMN2KMT2AMAPT | |
| SCHEMBL28007683 | 0.83 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KMT2AMAPTRAB9A | |
| SCHEMBL3947571 | 0.81 | POLB (0.54) | ALDH1A1SMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL28669741 | 0.79 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNATDP1TP53 | |
| SCHEMBL13011385 | 0.79 | HSD17B2 (0.53) | ALDH1A1GAASMN1; SMN2KMT2AMAPT | |
| SCHEMBL29617015 | 0.79 | TP53 (0.62) | ALDH1A1SMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL5651802 | 0.79 | ALDH1A1 (0.53) | ALDH1A1GAASMN1; SMN2KMT2AMAPT | |
| SCHEMBL13830792 | 0.79 | NPC1 (0.52) | ALDH1A1SMN1; SMN2MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142638-A1 | Ornithine derivatives as prostaglandin e2 agonists or antagonists | ASTELLAS PHARMA INC. (JP) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142638-A1 | Ornithine derivatives as prostaglandin e2 agonists or antagonists | PTGER4, OXER1, RXFP4 | ALDH1A1 1570/4885GAA 4769/4885SMN1; SMN2 3483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.