Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14494917 | 0.84 | ALDH1A1 (0.57) | ALDH1A1TDP1MAPTLMNAHTT | |
| SCHEMBL5652491 | 0.83 | ALDH1A1 (0.52) | ALDH1A1TDP1MAPTLMNAHTT | |
| SCHEMBL28669741 | 0.82 | ALDH1A1 (0.64) | ALDH1A1TDP1MAPTLMNAERN1 | |
| SCHEMBL11541099 | 0.82 | MAPT (0.53) | ALDH1A1TDP1MAPTLMNAHTT | |
| SCHEMBL7815751 | 0.81 | ERN1 (0.58) | ALDH1A1TDP1MAPTLMNAHTT | |
| SCHEMBL23041052 | 0.78 | L3MBTL1 (0.50) | TDP1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL14241162 | 0.78 | NR1H4 (0.53) | MAPTSMN1; SMN2L3MBTL1ERCC5FEN1 | |
| SCHEMBL28053324 | 0.78 | MAPT (0.50) | ALDH1A1TDP1MAPTLMNAHTT | |
| SCHEMBL8085526 | 0.77 | L3MBTL1 (0.49) | ALDH1A1TDP1MAPTLMNAHTT | |
| SCHEMBL14241374 | 0.77 | KAT6A (0.50) | ALDH1A1MAPTLMNASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104387277-A | Method for synthesizing 2-nitro-3-phenyl propiophenone | UNIV CHANGZHOU | 2015-03-04 | — | — | CN | claimed |
| CN-104387277-A | Method for synthesizing 2-nitro-3-phenyl propiophenone | UNIV CHANGZHOU | 2015-03-04 | — | — | CN | disclosed |
| CN-104387277-A | Method for synthesizing 2-nitro-3-phenyl propiophenone | UNIV CHANGZHOU | 2015-03-04 | — | — | CN | disclosed |
| CN-104387277-A | Method for synthesizing 2-nitro-3-phenyl propiophenone | UNIV CHANGZHOU | 2015-03-04 | — | — | CN | disclosed |