Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5652518 | 1.00 | CYP19A1 (0.45) | CYP19A1CYP26A1IDO1 | |
| SCHEMBL3964389 | 0.90 | CYP19A1 (0.47) | CYP19A1CYP26A1 | |
| SCHEMBL5542318 | 0.80 | TDP1 (0.55) | — | |
| SCHEMBL622656 | 0.80 | IDO1 (0.50) | CYP26A1IDO1 | |
| Ammonia Solution, Strong SCHEMBL8172708 | 0.78 | IDO1 (0.48) | CYP26A1IDO1 | |
| SCHEMBL3367622 | 0.77 | LTA4H (0.48) | IDO1 | |
| SCHEMBL3365060 | 0.77 | LTA4H (0.51) | IDO1 | |
| SCHEMBL1366152 | 0.77 | GBA1 (0.50) | CYP19A1 | |
| SCHEMBL6628369 | 0.75 | LTA4H (0.54) | — | |
| SCHEMBL7368042 | 0.75 | CYP26A1 (0.49) | CYP19A1CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070265270-A1 | Cinnoline derivatives as phosphodiesterase 10 inhibitors | MEMORY PHARMACEUTICALS CORPORATION | 2007-11-15 | — | — | US | claimed |
| US-20070265270-A1 | Cinnoline derivatives as phosphodiesterase 10 inhibitors | MEMORY PHARMACEUTICALS CORPORATION | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265270-A1 | Cinnoline derivatives as phosphodiesterase 10 inhibitors | PDE7A, PDE10A, PDE7B | CYP19A1 96/4885CYP26A1 1297/4885IDO1 182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.