Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 11/20 | 0.56 |
| ▸ | DRD3 | P35462 | 11/20 | 0.56 |
| ▸ | DRD4 | P21917 | 5/20 | 0.55 |
| ▸ | HTR1A | P08908 | 4/20 | 0.55 |
| ▸ | HTR2A | P28223 | 3/20 | 0.55 |
| ▸ | HTR2C | P28335 | 3/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5651513 | 0.89 | DRD2 (0.52) | SLC6A2SLC6A4DRD2DRD3DRD4 | |
| SCHEMBL5650125 | 0.84 | DRD2 (0.60) | SLC6A4DRD2DRD3DRD4HTR1A | |
| SCHEMBL5651330 | 0.80 | DRD2 (0.55) | DRD2DRD3DRD4HTR1AADRA2A | |
| SCHEMBL14514784 | 0.76 | DRD2 (0.62) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL5653993 | 0.76 | DRD3 (0.55) | SLC6A4DRD2DRD3DRD4KCNH2 | |
| SCHEMBL6053607 | 0.74 | DRD2 (0.94) | DRD2DRD3DRD4HTR1AKCNH2 | |
| SCHEMBL5653701 | 0.74 | DRD3 (0.58) | SLC6A4DRD2DRD3DRD4HTR2A | |
| SCHEMBL5650284 | 0.73 | DRD3 (0.58) | SLC6A4DRD2DRD3HTR1AHTR2A | |
| SCHEMBL5653116 | 0.73 | DRD3 (0.58) | SLC6A4DRD2DRD3HTR1AHTR2A | |
| SCHEMBL3086024 | 0.71 | DRD2 (1.00) | SLC6A2SLC6A4DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220769-B2 | Azolylbenzamides and analogues and their use for treating osteoporosis | NIKEM RESEARCH S.R.L. (IT) | 2007-05-22 | — | — | US | disclosed |
| US-20050038095-A1 | Azolylbenzamides and analogues and their use for treating osteoporosis | 3-V BIOSCIENCES, INC. | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038095-A1 | Azolylbenzamides and analogues and their use for treating osteoporosis | NR0B2, NR0B1, NCOR1 | SLC6A2 2541/4885SLC6A4 3737/4885DRD2 3803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.