Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319584 | 1.00 | LMNA (0.39) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL31365935 | 1.00 | LMNA (0.39) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL15563205 | 1.00 | LMNA (0.39) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL31365936 | 1.00 | LMNA (0.39) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL7759645 | 1.00 | LMNA (0.39) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL2047008 | 1.00 | LMNA (0.39) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL6239055 | 0.98 | LMNA (0.37) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL24592051 | 0.92 | PLA2G1B (0.44) | LMNAKDM4CPHF8ALDH1A1PLA2G1B | |
| SCHEMBL2036981 | 0.91 | LMNA (0.39) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL9945683 | 0.91 | ALDH1A1 (0.38) | LMNAKDM4CKDM4APHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109364-B2 | Group of anti-cancer compounds with specific structure and their production method | YANG ZHENHUA | 2006-09-19 | — | — | US | disclosed |
| EP-1259470-A4 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | YANG ZHENHUA (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20040034242-A1 | Group of anti-cancer compounds with specific structure and their production method | YANG ZHENHUA (US) | 2004-02-19 | — | — | US | disclosed |
| EP-1259470-A2 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | Yang, Zhenhua (US) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001059067-A2 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | YANG ZHENHUA (US) | 2001-08-16 | — | — | WO | disclosed |