Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319584 | 0.98 | LMNA (0.39) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL5652783 | 0.98 | LMNA (0.39) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL15563205 | 0.98 | LMNA (0.39) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL31365935 | 0.98 | LMNA (0.39) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL7759645 | 0.98 | LMNA (0.39) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL2047008 | 0.98 | LMNA (0.39) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL31365936 | 0.98 | LMNA (0.39) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL24592051 | 0.90 | PLA2G1B (0.44) | LMNAKDM4CPHF8ALDH1A1PLA2G1B | |
| SCHEMBL2036981 | 0.89 | LMNA (0.39) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL9945683 | 0.89 | ALDH1A1 (0.38) | LMNAKDM4CKDM4APHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014528-A1 | STRAIGHT-CHAIN AND BRANCHED-CHAIN LIPID COMPOUNDS AS SELECTIVE INHIBITORS OF CYCLOOXYGENASE-2, ANTI-INFLAMMATORY AGENTS, AND ANTI-CANCER AGENTS | YANG ZHENHUA (US) | 2005-02-17 | — | — | WO | disclosed |