Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16420939 | 0.87 | KDM4E (0.54) | SMN1; SMN2HPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL26023443 | 0.86 | CA1 (0.55) | SMN1; SMN2HPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL3607026 | 0.86 | HDAC3 (0.58) | SMN1; SMN2HPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL28631592 | 0.83 | LOXL2 (0.68) | SMN1; SMN2HPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL63426 | 0.83 | LOXL2 (0.68) | SMN1; SMN2HPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL15997457 | 0.82 | CRHBP (0.62) | SMN1; SMN2HPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL28529337 | 0.82 | LOXL2 (0.66) | SMN1; SMN2HPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL28533242 | 0.82 | LOXL2 (0.66) | SMN1; SMN2HPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL5893077 | 0.79 | LOXL2 (0.61) | SMN1; SMN2HPGDTSHRCYP4A11LOXL2 | |
| SCHEMBL481297 | 0.79 | LOXL2 (0.61) | SMN1; SMN2HPGDKDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257917-A1 | FLUORESCENT DYES, ENERGY TRANSFER COUPLES AND METHODS | MILLIPORE CORPORATION | 2006-11-16 | — | — | US | disclosed |
| US-7091348-B2 | Fluorescent dyes, energy transfer couples and methods | GUAVA TECHNOLOGIES, INC. (US) | 2006-08-15 | — | — | US | disclosed |
| EP-1539728-A2 | FLUORESCENT DYES, ENERGY TRANSFER COUPLES AND METHODS | Guava Technologies, Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20040073014-A1 | Fluorescent dyes, energy transfer couples and methods | EMD MILLIPORE CORPORATION | 2004-04-15 | — | — | US | disclosed |
| WO-2004003510-A2 | FLUORESCENT DYES, ENERGY TRANSFER COUPLES AND METHODS | GUAVA TECHNOLOGIES, INC. (US) | 2004-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060257917-A1 | FLUORESCENT DYES, ENERGY TRANSFER COUPLES AND METHODS | TIMM50, TIMM44, APEX1 | SMN1; SMN2 4268/4885HPGD 1380/4885KDM4E 2901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.