Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Racemethionine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | BHMT | Q93088 | 7/20 | 0.36 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | ARG1 | P05089 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Racemethionine SCHEMBL5653415 | 1.00 | RNPEP (0.42) | RNPEPANPEPENPEPMETAP2METAP1 | |
| Racemethionine SCHEMBL30353028 | 0.98 | RNPEP (0.41) | RNPEPANPEPENPEPMETAP2METAP1 | |
| Racemethionine SCHEMBL15111375 | 0.96 | RNPEP (0.42) | RNPEPANPEPENPEPMETAP2METAP1 | |
| Racemethionine SCHEMBL3898448 | 0.96 | RNPEP (0.42) | RNPEPANPEPENPEPMETAP2METAP1 | |
| Racemethionine SCHEMBL5150216 | 0.96 | RNPEP (0.42) | RNPEPANPEPENPEPMETAP2METAP1 | |
| Racemethionine SCHEMBL18886804 | 0.96 | RNPEP (0.42) | RNPEPANPEPENPEPMETAP2METAP1 | |
| Racemethionine SCHEMBL17473910 | 0.96 | RNPEP (0.42) | RNPEPANPEPENPEPMETAP2METAP1 | |
| Racemethionine SCHEMBL20553497 | 0.96 | — | — | |
| Racemethionine SCHEMBL21221265 | 0.96 | RNPEP (0.42) | RNPEPANPEPENPEPMETAP2METAP1 | |
| Racemethionine SCHEMBL3898443 | 0.96 | RNPEP (0.42) | RNPEPANPEPENPEPMETAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6287627-B1 | SPRAY DRYING; FORMING POWDER | DEGUSSA AG (DE) | 2001-09-11 | — | — | US | claimed |
| EP-0215735-B1 | VETERINARY-MEDICAL KIT FOR A RAPID TEST TO DETERMINE THE CALCIUM CONTENT OF BLOOD | Dr. Ernst Gräub AG (CH) | 1990-06-13 | — | — | EP | claimed |
| US-11913875-B2 | Method for the identification of an incorrectly calibrated or non-calibrated infrared spectrometer | EVONIK OPERATIONS GMBH (DE) | 2024-02-27 | — | — | US | disclosed |
| EP-3899462-B1 | METHOD FOR THE IDENTIFICATION OF AN INCORRECTLY CALIBRATED OR NON-CALIBRATED INFRARED SPECTROMETER AND FOR THE CORRECTION OF A SPECTRUM RECORDED ON AN INCORRECTLY OR NON-CALIBRATED INFRARED SPECTROMETER | EVONIK OPERATIONS GMBH (DE) | 2022-06-22 | — | — | EP | disclosed |
| US-20220026350-A1 | METHOD FOR THE IDENTIFICATION OF AN INCORRECTLY CALIBRATED OR NON-CALIBRATED INFRARED SPECTROMETER | EVONIK OPERATIONS GMBH (SE) | 2022-01-27 | — | — | US | disclosed |
| EP-3899462-A1 | METHOD FOR THE IDENTIFICATION OF AN INCORRECTLY CALIBRATED OR NON-CALIBRATED INFRARED SPECTROMETER | Evonik Operations GmbH (DE) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020126869-A1 | METHOD FOR THE IDENTIFICATION OF AN INCORRECTLY CALIBRATED OR NON-CALIBRATED INFRARED SPECTROMETER | EVONIK OPERATIONS GMBH (DE) | 2020-06-25 | — | — | WO | disclosed |
| US-10638785-B2 | Liquid dietary supplement formulation compositions | Watermins, LLC (US) | 2020-05-05 | — | — | US | disclosed |
| US-20190223487-A1 | LIQUID DIETARY SUPPLEMENT FORMULATION COMPOSITIONS | Watermins, LLC | 2019-07-25 | — | — | US | disclosed |
| EP-3495346-A1 | METHOD FOR THE PRODUCTION OF CALCIUM METHIONINATE | Evonik Degussa GmbH (DE) | 2019-06-12 | — | — | EP | disclosed |
| US-10251412-B2 | Liquid dietary supplement formulation compositions | WATERMINS LLC | 2019-04-09 | — | — | US | disclosed |
| US-5672745-A | HYDROLYSIS OF METHONINE NITRILE TO METHONINE OR SALTS IN PRESENCE OF KETONE, FOLLOWED BY SAPONIFICATION WITH BASE TO FORM CRUDE METHIONINE PDRODUCT MIXTURE, AND SIMULTANEOUS DRAWING OF AMMONIA, KETONE AND WATER | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1997-09-30 | — | — | US | disclosed |
| US-5631031-A | FOOD SUPPLEMENTS FOR RUMINANTS AND HUMANS AS CALCIUM SALTS | MEADE THOMAS L (US) | 1997-05-20 | — | — | US | disclosed |
| EP-0758563-A1 | OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT | NIPPON OIL COMPANY, LTD. (JP) | 1997-02-19 | — | — | EP | disclosed |
| EP-0514451-B1 | DIETARY SUPPLEMENTS COMPRISING VITAMINS AND MINERALS | LIFESCIENCE CORP (US) | 1997-01-15 | — | — | EP | disclosed |
| WO-1996002624-A1 | A CLEANING KIT AND A CLEANING COMPOSITION AND METHODS OF USE | SO-SAFE SPECIALTY PRODUCTS PTY. LTD. (AU) | 1996-02-01 | — | — | WO | disclosed |
| CN-1104890-A | Cation-complexed polysacharides | HERCULES INC (US) | 1995-07-12 | — | — | CN | disclosed |
| EP-0648495-A2 | Cation-complexed polysaccharides | HERCULES INCORPORATED (US) | 1995-04-19 | — | — | EP | disclosed |
| EP-0514451-A1 | DIETARY SUPPLEMENTS COMPRISING VITAMINS AND MINERALS. | UNIV TEXAS (US) | 1992-11-25 | — | — | EP | disclosed |
| WO-1991011117-A2 | DIETARY SUPPLEMENTS COMPRISING VITAMINS AND MINERALS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1991-08-08 | — | — | WO | disclosed |