SCHEMBL5654311

SCHEMBL5654311

O=CC1C(C(=O)O)=Cc2cccc3cccc1c23

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
HSD17B10 Q99714 1/20 0.34
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11127902 0.78 MEN1 (0.36) MEN1KMT2AHSD17B10MAPTMAPK1
SCHEMBL547754 0.76 MEN1 (0.34) MEN1KMT2AMAPTMAPK1
SCHEMBL8770837 0.71 MEN1 (0.30) MEN1KMT2AMAPTMAPK1
SCHEMBL6741677 0.69 KDM4E (0.42)
SCHEMBL6741675 0.69 KDM4E (0.42)
SCHEMBL1666659 0.68 MTNR1A (0.34) MEN1KMT2AHSD17B10MAPTMAPK1
SCHEMBL11409724 0.68 ATM (0.37) MEN1KMT2AMAPTMAPK1
SCHEMBL547553 0.68 HSD17B10 (0.39) MEN1KMT2AHSD17B10MAPT
SCHEMBL1666386 0.67 EPHX1 (0.40) MEN1KMT2AMAPTMAPK1EPHX1
SCHEMBL9422190 0.65 KDM4E (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0907773-B1 HIGH SURFACE AREA NANOFIBERS HYPERION CATALYSIS INT (US) 2006-08-16 EP disclosed
US-6099960-A PYROLIZING A POLYMERIC COATING SUBSTANCE PROVIDED ON THE OUTER SURFACE OF THE CARBON NANOFIBER AT A TEMPERATURE BELOW THE TEMPERATURE AT WHICH THE POLYMERIC COATING SUBSTANCE MELTS HYPERION CATALYSIS INTERNATIONAL (US) 2000-08-08 US disclosed
EP-0907773-A4 1999-05-12 EP disclosed
EP-0907773-A1 HIGH SURFACE AREA NANOFIBERS HYPERION CATALYSIS INTERNATIONAL, INC. (US) 1999-04-14 EP disclosed
WO-1997043473-A1 HIGH SURFACE AREA NANOFIBERS HYPERION CATALYSIS INTERNATIONAL, INC. (US) 1997-11-20 WO disclosed