SCHEMBL8770837

SCHEMBL8770837

C=CCC1=Cc2cccc3cccc(c23)C1C=O

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27516984 0.79
SCHEMBL28085016 0.79 GABRA1 (0.30)
SCHEMBL6919714 0.78
SCHEMBL11798178 0.76 MEN1 (0.31) MEN1MAPTMAPK1KMT2A
SCHEMBL11499177 0.75 MEN1 (0.30) MEN1MAPTMAPK1KMT2A
SCHEMBL547754 0.74 MEN1 (0.34) MEN1MAPTMAPK1KMT2A
SCHEMBL11555148 0.74 MEN1 (0.31) MEN1MAPTMAPK1KMT2A
SCHEMBL11763096 0.74 MTNR1A (0.36) MEN1MAPTKMT2A
SCHEMBL8754428 0.72 CES2 (0.32)
SCHEMBL4552783 0.71 MEN1 (0.31) MEN1MAPTMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0670844-B1 ALDONAMIDES AND THEIR USE AS SURFACTANTS UNILEVER PLC (GB) 1997-10-01 EP disclosed
US-5653970-A CLEANING COMPOUNDS; COSMETICS LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-08-05 US disclosed
US-5641480-A ENHANCED STABILITY AND/OR VISCOSITY, CLARITY LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-06-24 US disclosed
US-5624906-A Oral hygiene compositions comprising heteroatom containing alkyl aldonamide compounds LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-04-29 US disclosed
US-5521293-A Heteroatom containing alkyl aldonamide compounds as superior foaming, more soluble nonionic surfactants and a process for their manufacture LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1996-05-28 US disclosed
EP-0670844-A1 ALDONAMIDES AND THEIR USE AS SURFACTANTS. UNILEVER PLC (GB) 1995-09-13 EP disclosed
WO-1994012511-A1 ALDONAMIDES AND THEIR USE AS SURFACTANTS UNILEVER PLC (GB) 1994-06-09 WO disclosed