Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4929727 | 0.86 | STAT3 (0.41) | STAT3CA12CA1CA9ALDH1A1 | |
| SCHEMBL4921663 | 0.86 | STAT3 (0.41) | STAT3CA12CA1CA9ALDH1A1 | |
| SCHEMBL5989974 | 0.86 | STAT3 (0.41) | STAT3CA12CA1CA9ALDH1A1 | |
| SCHEMBL4921650 | 0.86 | STAT3 (0.41) | STAT3CA12CA1CA9ALDH1A1 | |
| SCHEMBL5477848 | 0.85 | CA12 (0.44) | STAT3CA12CA1CA9ALDH1A1 | |
| SCHEMBL5474740 | 0.85 | CA12 (0.44) | STAT3CA12CA1CA9ALDH1A1 | |
| SCHEMBL21239935 | 0.85 | ALDH1A1 (0.41) | STAT3CA12CA1CA9ALDH1A1 | |
| SCHEMBL3940918 | 0.85 | STAT3 (0.40) | STAT3CA12CA1CA9ALDH1A1 | |
| SCHEMBL3940922 | 0.85 | STAT3 (0.40) | STAT3CA12CA1CA9ALDH1A1 | |
| SCHEMBL4303888 | 0.85 | CA12 (0.44) | STAT3CA12CA1CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262310-B2 | Process for preparing 3-hydroxythiolane | DAISO CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20050222433-A1 | Process for preparing 3-hydroxythiolane | OSAKA SODA CO., LTD. (JP) | 2005-10-06 | — | — | US | disclosed |
| EP-1582518-A1 | Process for preparing 3-Hydroxythiolane | DAISO CO., LTD. (JP) | 2005-10-05 | — | — | EP | disclosed |
| EP-0452143-B1 | Process for preparing optically active 3-hydroxypyrrolidine derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 1994-10-05 | — | — | EP | disclosed |
| US-5144042-A | PROCESS FOR PREPARING OPTICALLY ACTIVE 3-HYDROXYPYRROLIDINE DERIVATIVES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1992-09-01 | — | — | US | disclosed |
| EP-0452143-A2 | Process for preparing optically active 3-hydroxypyrrolidine derivatives | Takasago International Corporation (JP) | 1991-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222433-A1 | Process for preparing 3-hydroxythiolane | HACL2, HAX1, SQLE | STAT3 4694/4885CA12 4450/4885CA1 4030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.