Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.55 |
| ▸ | PRNP | P04156 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30822036 | 1.00 | RAB9A (0.60) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL8859833 | 0.81 | NPC1 (0.62) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL1359254 | 0.79 | MAOB (0.50) | CYP1A2ALOX5 | |
| SCHEMBL27512292 | 0.79 | NPC1 (0.60) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL19608995 | 0.79 | NPC1 (0.60) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL4078645 | 0.79 | NPC1 (0.60) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL29860529 | 0.79 | NPC1 (0.60) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL2386082 | 0.79 | NPC1 (0.60) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL26622001 | 0.79 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL7362748 | 0.79 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250326777-A1 | COMPOUNDS, COMPOSITIONS AND METHODS THEREOF | HEPAITECH BEIJING BIOPHARMA TECH CO LTD (CN) | 2025-10-23 | — | — | US | disclosed |
| US-20220304958-A1 | SMALL MOLECULE INHIBITORS OF A PROTEIN COMPLEX | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-09-29 | — | — | US | disclosed |
| WO-2020247608-A1 | SMALL MOLECULE INHIBITORS OF A PROTEIN COMPLEX | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-12-10 | — | — | WO | disclosed |
| CN-109843856-A | KRAS G12C inhibitor | 米拉蒂治疗股份有限公司 | 2019-06-04 | — | — | CN | disclosed |
| EP-3458445-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2019-03-27 | — | — | EP | disclosed |
| WO-2017201161-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2017-11-23 | — | — | WO | disclosed |
| US-7291739-B2 | 3, 4-disubstituted pyridine compounds; | IMPERIAL INNOVATIONS LIMITED (GB) | 2007-11-06 | — | — | US | disclosed |
| US-7291739-B2 | 3, 4-disubstituted pyridine compounds; | IMPERIAL INNOVATIONS LIMITED (GB) | 2007-11-06 | — | — | US | disclosed |
| US-20040127740-A1 | Chiral catalysts for asymmetric acylation and related transformations | SHEFFIELD UNIVERSITY OF WESTERN BANK | 2004-07-01 | — | — | US | disclosed |
| US-6743922-B2 | 3-SUBSTITUENT HIGHLY RESISTANT TO ROTATION-4-TERTIARY AMINO-PYRIDINE | UNIVERSITY OF SHEFFIELD (GB) | 2004-06-01 | — | — | US | disclosed |
| EP-1233828-B1 | CHIRAL CATALYSTS FOR ASYMMETRIC ACYLATION AND RELATED TRANSFORMATIONS | UNIV SHEFFIELD (GB) | 2004-05-06 | — | — | EP | disclosed |
| US-20030017942-A1 | Chiral catalysts for asymmetric acylation and related transformations | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2003-01-23 | — | — | US | disclosed |
| EP-1233828-A2 | CHIRAL CATALYSTS FOR ASYMMETRIC ACYLATION AND RELATED TRANSFORMATIONS | THE UNIVERSITY OF SHEFFIELD (GB) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001039884-A2 | CHIRAL CATALYSTS FOR ASYMMETRIC ACYLATION AND RELATED TRANSFORMATIONS | UNIVERSITY OF SHEFFIELD (GB) | 2001-06-07 | — | — | WO | disclosed |
| US-5872301-A | Bifunctional precursors for the preparation of liquid crystals | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030017942-A1 | Chiral catalysts for asymmetric acylation and related transformations | NR4A1, HAT1, NR2C2 | RAB9A 3889/4885NPC1 1481/4885SMN1; SMN2 2352/4885 |
| US-20040127740-A1 | Chiral catalysts for asymmetric acylation and related transformations | NR4A1, NR0B1, NR2C2 | RAB9A 3977/4885NPC1 1555/4885SMN1; SMN2 2094/4885 |
| US-20250326777-A1 | COMPOUNDS, COMPOSITIONS AND METHODS THEREOF | MRGPRX4, MRGPRX1, MRGPRX2 | RAB9A 1008/4885NPC1 56/4885SMN1; SMN2 171/4885 |
| US-20220304958-A1 | SMALL MOLECULE INHIBITORS OF A PROTEIN COMPLEX | SERBP1, PPHLN1, VCAM1 | RAB9A 2777/4885NPC1 1712/4885SMN1; SMN2 4708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.