SCHEMBL565501

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL564785	0.94	ESR1 (0.46)	ESR1RORCKLF10HCAR3CA12
	SCHEMBL565156	0.93	CA12 (0.41)	ESR1RORCKLF10HCAR3CA12
	SCHEMBL564566	0.93	ALDH1A1 (0.45)	ESR1RORCKLF10HCAR3ESR2
	SCHEMBL565593	0.90	ESR1 (0.43)	ESR1RORCKLF10HCAR3CA12
	SCHEMBL566137	0.89	ESR1 (0.39)	ESR1RORCKLF10HCAR3CA12
	SCHEMBL565866	0.87	ESR1 (0.46)	ESR1RORCKLF10HCAR3CA12
	SCHEMBL566122	0.82	ESR1 (0.46)	ESR1RORCKLF10CA12CA1
	SCHEMBL564549	0.81	ALDH1A1 (0.45)	ESR1RORCKLF10ESR2ALDH1A1
	SCHEMBL565833	0.81	CA12 (0.41)	ESR1RORCKLF10HCAR3CA12
	SCHEMBL565964	0.79	ESR1 (0.43)	ESR1RORCKLF10ESR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.