Sugi Predict

Sugi Predict / Compounds / SCHEMBL565593

SCHEMBL565593

SCHEMBL565593

C=CCNc1ccc(C(C)(C)c2cccc(O)c2)cc1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 4/20 0.43
▸ ESR2 Q92731 3/20 0.43
▸ CNR1 P21554 3/20 0.36
▸ CNR2 P34972 3/20 0.36
▸ ALDH1A1 P00352 3/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ RORC P51449 1/20 0.35
▸ CYP3A4 P08684 2/20 0.35
▸ KLF10 Q13118 1/20 0.35
▸ ACHE P22303 1/20 0.34
▸ OPRM1 P35372 2/20 0.33
▸ OPRD1 P41143 2/20 0.33
▸ OPRK1 P41145 2/20 0.33
▸ KIF11 P52732 2/20 0.32
▸ HCAR3 P49019 1/20 0.32
▸ NLRP3 Q96P20 1/20 0.32
▸ AR P10275 1/20 0.32
▸ HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL565501 0.90 ESR1 (0.42) ESR1ESR2CNR1CNR2ALDH1A1
SCHEMBL565964 0.90 ESR1 (0.43) ESR1ESR2CNR1CNR2ALDH1A1
SCHEMBL564566 0.89 ALDH1A1 (0.45) ESR1ESR2CNR1CNR2ALDH1A1
SCHEMBL566137 0.88 ESR1 (0.39) ESR1ESR2CNR1CNR2ALDH1A1
SCHEMBL564785 0.88 ESR1 (0.46) ESR1ESR2CNR1CNR2ALDH1A1
SCHEMBL565156 0.84 CA12 (0.41) ESR1ESR2CNR1CNR2ALDH1A1
SCHEMBL565866 0.79 ESR1 (0.46) ESR1ESR2ALDH1A1KDM4ESMN1; SMN2
SCHEMBL564549 0.78 ALDH1A1 (0.45) ESR1ESR2CNR1CNR2ALDH1A1
SCHEMBL565071 0.78 ESR1 (0.39) ESR1ESR2CNR1CNR2ALDH1A1
SCHEMBL566122 0.77 ESR1 (0.46) ESR1ESR2ALDH1A1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 — — US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 — — US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 — — US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 — — US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 — — US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 — — US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 ESR1 1065/4885ESR2 1253/4885CNR1 574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.