Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809943 | 0.86 | KMT2A (0.37) | KMT2ACYP2D6LMNAOPRK1 | |
| SCHEMBL9039578 | 0.81 | ESR1 (0.38) | ESR1ESR2PDCD1CD274GRIN2B | |
| SCHEMBL14440852 | 0.78 | MMP1 (0.41) | KMT2ACYP2D6ADRB1RAB9A | |
| SCHEMBL4801749 | 0.75 | KMT2A (0.35) | KMT2ACYP2D6LMNAOPRK1 | |
| SCHEMBL886985 | 0.75 | KMT2A (0.35) | KMT2ACYP2D6LMNAOPRK1 | |
| SCHEMBL976664 | 0.73 | HSD11B1 (0.32) | ESR1ESR2PDCD1CD274 | |
| SCHEMBL13008873 | 0.73 | SLC6A2 (0.38) | KMT2ACYP2D6KCNH2ADRA2AHTR2A | |
| SCHEMBL2809617 | 0.73 | GAA (0.31) | KMT2A | |
| SCHEMBL8853589 | 0.72 | HPGD (0.31) | — | |
| SCHEMBL13008720 | 0.71 | TACR1 (0.39) | KMT2ACYP2D6ADRA2ALMNAADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253232-B2 | Thermoplastic compositions with enhanced melt flow and compatibility | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-08-07 | — | — | US | disclosed |
| US-20050288435-A1 | Thermoplastic compositions with enhanced melt flow and compatibility | CIBA SPECIALTY CHEMICALS CORP. | 2005-12-29 | — | — | US | disclosed |
| EP-1543077-A1 | THERMOPLASTIC COMPOSITIONS WITH ENHANCED MELT FLOW AND COMPATIBILITY | Ciba SC Holding AG (CH) | 2005-06-22 | — | — | EP | disclosed |
| WO-2004029156-A1 | THERMOPLASTIC COMPOSITIONS WITH ENHANCED MELT FLOW AND COMPATIBILITY | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-04-08 | — | — | WO | disclosed |