SCHEMBL886985

SCHEMBL886985

CCC1(CC)CC(O)CC(C)(C)N1OC(C)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.35
KCNA3 P22001 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD11B1 P28845 2/20 0.32
S1PR5 Q9H228 2/20 0.32
S1PR1 P21453 1/20 0.32
TSHR P16473 3/20 0.32
CYP2D6 P10635 1/20 0.31
OPRM1 P35372 2/20 0.31
OPRD1 P41143 2/20 0.31
OPRK1 P41145 2/20 0.31
OPRL1 P41146 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6809943 0.88 KMT2A (0.37) KMT2AKCNA3ALOX15HSD11B1S1PR5
SCHEMBL4801749 0.87 KMT2A (0.35) KMT2AKCNA3ALOX15HSD11B1S1PR5
SCHEMBL5341504 0.85 TACR1 (0.37)
SCHEMBL17189635 0.85
SCHEMBL27550616 0.81
SCHEMBL5342996 0.81 KMT2A (0.53) KMT2AS1PR5S1PR1TSHRCYP2D6
SCHEMBL27550813 0.81 CYP2D6 (0.31) CYP2D6LMNA
SCHEMBL5347557 0.80 KMT2A (0.41) KMT2AS1PR5S1PR1TSHRCYP2D6
SCHEMBL5344687 0.80 TSHR (0.41) KMT2AS1PR5S1PR1TSHRCYP2D6
SCHEMBL5346731 0.80 TACR1 (0.43) KMT2AALOX15TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10316114-B2 End-functionalized polymers BASF SE (DE) 2019-06-11 US disclosed
EP-2552971-B1 END-FUNCTIONALIZED POLYMERS BASF SE (DE) 2014-07-02 EP disclosed
US-8669336-B2 Fluoro levelling agents BASF SE (DE) 2014-03-11 US disclosed
US-8664324-B2 Pigment dispersants with modified copolymers BASF SE (DE) 2014-03-04 US disclosed
US-8664324-B2 Pigment dispersants with modified copolymers BASF SE (DE) 2014-03-04 US disclosed
US-20130030071-A1 END-FUNCTIONALIZED POLYMERS BASF SE (DE) 2013-01-31 US disclosed
US-20130030071-A1 END-FUNCTIONALIZED POLYMERS BASF SE (DE) 2013-01-31 US disclosed
EP-2247678-B1 FLUORO LEVELLING AGENTS BASF SE (DE) 2011-11-30 EP disclosed
WO-2011120947-A1 END-FUNCTIONALIZED POLYMERS BASF SE (DE) 2011-10-06 WO disclosed
US-20110144260-A1 PIGMENT DISPERSANTS WITH MODIFIED COPOLYMERS BASF SE (DE) 2011-06-16 US disclosed
US-20050143539-A1 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides NESVADBA PETER (CH) 2005-06-30 US disclosed
US-20050131177-A1 1-Alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators KRAMER ANDREAS (SE) 2005-06-16 US disclosed
US-6891008-B2 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. (US) 2005-05-10 US disclosed
US-6683142-B2 PROVIDE POLYMERIC RESIN PRODUCTS HAVING LOW POLYDISPERSITY. CIBA SPECIALTY CHEMICALS CORPORATION 2004-01-27 US disclosed
US-20030220423-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators KRAMER ANDREAS (CH) 2003-11-27 US disclosed
US-6624306-B2 Stabilizer for addition polymer CIBA SPECIALTY CHEMICALS CORPORATION 2003-09-23 US disclosed
US-20030166939-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides NESVADBA PETER (CH) 2003-09-04 US disclosed
US-20030065184-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. 2003-04-03 US disclosed
US-20020107397-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators KRAMER ANDREAS (CH) 2002-08-08 US disclosed
US-6353107-B1 FREE RADICAL CATALYSTS FOR ADDITION POLYMERIZATION; NARROW MOLECULAR WEIGHT DISTRIBUTION; HIGH PURITY AND COLORLESS CIBA SPECIALTY CHEMICALS CORPORATION 2002-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030166939-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides ALKBH2, NFE2L2, DPYSL2 KMT2A 1595/4885KCNA3 2729/4885ALOX15 125/4885
US-20050131177-A1 1-Alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators PYM1, PTGER1, CBR1 KMT2A 3106/4885KCNA3 1523/4885ALOX15 128/4885
US-20020107397-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators CBR1, PYM1, ELOC KMT2A 3370/4885KCNA3 2435/4885ALOX15 112/4885
US-20050143539-A1 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides ALKBH2, NFE2L2, DPYSL2 KMT2A 1595/4885KCNA3 2729/4885ALOX15 125/4885
US-20030065184-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides ALKBH2, NFE2L2, DPYSL2 KMT2A 1595/4885KCNA3 2729/4885ALOX15 125/4885
US-20030220423-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators PYM1, ELOC, CBR1 KMT2A 3222/4885KCNA3 2276/4885ALOX15 114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.