Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580690 | 0.75 | PDK1 (0.47) | ALDH1A1TDP1 | |
| SCHEMBL317481 | 0.73 | ALDH1A1 (0.56) | ALDH1A1TDP1 | |
| SCHEMBL4521634 | 0.72 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL17046393 | 0.70 | MAPT (0.49) | ALDH1A1TDP1 | |
| SCHEMBL16953775 | 0.69 | MEN1 (0.34) | ALDH1A1TDP1 | |
| SCHEMBL10819050 | 0.69 | ALDH1A1 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL21268246 | 0.69 | NPC1 (0.39) | ALDH1A1 | |
| SCHEMBL21268339 | 0.69 | NPC1 (0.50) | ALDH1A1 | |
| SCHEMBL8177420 | 0.68 | POLB (0.39) | ALDH1A1TDP1 | |
| SCHEMBL20138635 | 0.68 | SMN1; SMN2 (0.41) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254917-A1 | INTRACELLULAR RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INC. | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254917-A1 | INTRACELLULAR RECEPTOR MODULATOR COMPOUNDS AND METHODS | CASR, GRK2, RYR2 | ALDH1A1 4580/4885TDP1 4046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.