Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5655244 | 0.86 | NAAA (0.54) | NAAAL3MBTL1CA2MLYCDHPGD | |
| SCHEMBL6022127 | 0.82 | NAAA (0.56) | NAAAL3MBTL1CA2MLYCDHPGD | |
| SCHEMBL19326796 | 0.81 | NAAA (0.71) | NAAAL3MBTL1CA2MLYCDSMN1; SMN2 | |
| SCHEMBL9978782 | 0.81 | NAAA (0.71) | NAAAL3MBTL1CA2MLYCDSMN1; SMN2 | |
| SCHEMBL1977288 | 0.81 | NAAA (0.71) | NAAAL3MBTL1CA2MLYCDSMN1; SMN2 | |
| SCHEMBL9979011 | 0.81 | NAAA (0.71) | NAAAL3MBTL1CA2MLYCDSMN1; SMN2 | |
| SCHEMBL6437809 | 0.81 | NAAA (0.71) | NAAAL3MBTL1CA2MLYCDSMN1; SMN2 | |
| SCHEMBL9979317 | 0.81 | NAAA (0.71) | NAAAL3MBTL1CA2MLYCDSMN1; SMN2 | |
| SCHEMBL1978767 | 0.81 | NAAA (0.71) | NAAAL3MBTL1CA2MLYCDSMN1; SMN2 | |
| SCHEMBL19326794 | 0.81 | NAAA (0.71) | NAAAL3MBTL1CA2MLYCDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185118-A1 | Use of methylene amide derivatives in cardiovascular disorders | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2007-08-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185118-A1 | Use of methylene amide derivatives in cardiovascular disorders | TNNI3, TNNT2, ADM2 | NAAA 684/4885L3MBTL1 2368/4885CA2 2960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.