SCHEMBL5655326

SCHEMBL5655326

C[C@H](N)C(=O)Oc1cscn1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25007603 0.76 CA2 (0.38) KDM4EALDH1A1TSHR
SCHEMBL1119624 0.74
SCHEMBL23283974 0.72 ALDH1A1 (0.45) KDM4EALDH1A1TSHR
SCHEMBL19031975 0.71 ELANE (0.40) KDM4EALDH1A1TSHR
SCHEMBL20757083 0.71
SCHEMBL13134171 0.70 KDM4E (0.36) KDM4EALDH1A1TSHR
SCHEMBL16636387 0.69 KDM4E (0.52) KDM4EALDH1A1TSHR
SCHEMBL22660992 0.69 PIK3CD (0.32)
SCHEMBL3718331 0.69 SMN1; SMN2 (0.43) KDM4EALDH1A1TSHR
SCHEMBL29016737 0.69 NOS2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020230780-A1 Ras INHIBITORY PEPTIDE 一丸ファルコス株式会社 2020-11-19 WO claimed
CN-110746868-A Water-based non-stick bactericidal environment-friendly paint and preparation method thereof 湖南辰砾新材料有限公司 2020-02-04 CN claimed
CN-101903010-B Topical compositions containing non-proteogenic amino acids and methods of treating skin AVON PROD INC 2014-11-26 CN claimed
CN-101903010-A Topical compositions containing non-proteogenic amino acids and methods of treating skin AVON PROD INC 2010-12-01 CN claimed
CN-1234735-A Method for treating skin pigmentation JOHNSON & JOHNSON CONSUMER (US) 1999-11-10 CN claimed
WO-1992007845-A1 DERIVATIVES OF AMINO ACIDS AS INHIBITORS OF RENIN, METHODS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-14 WO claimed
EP-0483403-A1 Derivatives of amino acids as inhibitors of renin, methods for their preparation, medicaments containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-06 EP claimed
CN-110746868-A Water-based non-stick bactericidal environment-friendly paint and preparation method thereof 湖南辰砾新材料有限公司 2020-02-04 CN disclosed
CN-106573073-A FAP-activated therapeutics and uses related thereto 塔夫茨大学信托人 2017-04-19 CN disclosed
CN-101903010-B Topical compositions containing non-proteogenic amino acids and methods of treating skin AVON PROD INC 2014-11-26 CN disclosed
US-8709998-B2 Peptide vectors IPSEN PHARMA S.A.S. (FR) 2014-04-29 US disclosed
CN-101903010-A Topical compositions containing non-proteogenic amino acids and methods of treating skin AVON PROD INC 2010-12-01 CN disclosed
CN-101466408-A Polycation-polyanion complexes, compositions, and methods of use thereof AERIS THERAPEUTICS INC (US) 2009-06-24 CN disclosed
CN-1234735-A Method for treating skin pigmentation JOHNSON & JOHNSON CONSUMER (US) 1999-11-10 CN disclosed
CN-1124927-A Analogs of peptide YY and uses thereof UNIV CINCINNATI (US) 1996-06-19 CN disclosed
WO-1992007845-A1 DERIVATIVES OF AMINO ACIDS AS INHIBITORS OF RENIN, METHODS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-14 WO disclosed
EP-0483403-A1 Derivatives of amino acids as inhibitors of renin, methods for their preparation, medicaments containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-06 EP disclosed
EP-0439556-A1 HETEROCYCLIC PEPTIDE RENIN INHIBITORS ABBOTT LABORATORIES (US) 1991-08-07 EP disclosed
WO-1990005531-A1 METHOD FOR TREATING VASCULAR DISEASES ABBOTT LABORATORIES (US) 1990-05-31 WO disclosed
WO-1990004917-A1 HETEROCYCLIC PEPTIDE RENIN INHIBITORS ABBOTT LABORATORIES (US) 1990-05-17 WO disclosed