Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5655435 | 0.95 | TLR8 (0.59) | ALDH1A1POLBKMT2ATLR8AGTR1 | |
| SCHEMBL5656069 | 0.89 | ALDH1A1 (0.44) | ALDH1A1POLBKMT2ATLR8AGTR1 | |
| SCHEMBL17599652 | 0.86 | ALDH1A1 (0.56) | ALDH1A1POLBKMT2ATLR8AGTR1 | |
| SCHEMBL6115119 | 0.85 | ALDH1A1 (0.69) | ALDH1A1POLBKMT2ATLR8KCNH2 | |
| SCHEMBL9935809 | 0.85 | ALDH1A1 (0.63) | ALDH1A1POLBKMT2ATLR8AGTR1 | |
| SCHEMBL329466 | 0.85 | ALDH1A1 (0.63) | ALDH1A1POLBKMT2ATLR8KCNH2 | |
| SCHEMBL6115033 | 0.83 | ALDH1A1 (0.61) | ALDH1A1POLBKMT2ATLR8AGTR1 | |
| SCHEMBL4361611 | 0.83 | ALDH1A1 (0.61) | ALDH1A1POLBKMT2ATLR8AGTR1 | |
| SCHEMBL1049122 | 0.83 | ALDH1A1 (0.61) | ALDH1A1POLBKMT2ATLR8AGTR1 | |
| Iodide SCHEMBL4267902 | 0.83 | ALDH1A1 (0.61) | ALDH1A1POLBKMT2ATLR8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262185-B2 | Benzazepine derivative, process for producing the same, and use | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20040235822-A1 | Benzazepine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-11-25 | — | — | US | disclosed |
| EP-1422228-A1 | BENZAZEPINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Chemical Industries, Ltd. (JP) | 2004-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235822-A1 | Benzazepine derivative, process for producing the same, and use | CYP1B1, CYP1A1, CYP2E1 | ALDH1A1 519/4885POLB 3578/4885KMT2A 391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.