Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5654667 | 0.88 | HTR7 (0.53) | HTR7HTR1AMAPTTP53KCNH2 | |
| SCHEMBL5655916 | 0.85 | MAPT (0.50) | DRD2ADRA1ADRD3HTR1AMAPT | |
| SCHEMBL5657837 | 0.85 | HTR1A (0.56) | HTR7DRD2ADRA1AHTR1AMAPT | |
| SCHEMBL6415441 | 0.85 | MAPT (0.52) | HTR7DRD2DRD3HTR1AMAPT | |
| SCHEMBL5657971 | 0.85 | KCNH2 (0.50) | HTR7DRD2DRD3HTR1AMAPT | |
| SCHEMBL5657779 | 0.85 | HTR1A (0.59) | HTR7HTR1AMAPTLMNATSHR | |
| SCHEMBL5656134 | 0.85 | HTR1A (0.48) | HTR7ADRA1AHTR1AMAPTOPRM1 | |
| SCHEMBL6753307 | 0.84 | HTR7 (0.43) | HTR7DRD2ADRA1AHTR1AOPRM1 | |
| SCHEMBL5656201 | 0.84 | HTR1A (0.55) | HTR7DRD2ADRA1ADRD3HTR1A | |
| SCHEMBL6416890 | 0.82 | DRD2 (0.52) | DRD2ADRA1ADRD3MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238693-B2 | Aryl carbamate derivatives, preparation and use thereof | CEREP (FR) | 2007-07-03 | — | — | US | disclosed |