Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5660210 | 0.74 | SMN1; SMN2 (0.55) | ALDH1A1KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL5658844 | 0.74 | CXCR1 (0.53) | ALDH1A1KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL3149056 | 0.74 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL8234531 | 0.72 | RAB9A (0.63) | ALDH1A1KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL23361502 | 0.72 | MAPK14 (0.46) | LMNARAB9A | |
| SCHEMBL29268467 | 0.72 | MAPT (0.64) | ALDH1A1KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL15702587 | 0.70 | MEN1 (0.60) | ALDH1A1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL29268504 | 0.70 | RAB9A (0.60) | ALDH1A1KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL3130610 | 0.69 | RAB9A (0.68) | ALDH1A1KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL5660133 | 0.69 | NOTUM (0.67) | ALDH1A1L3MBTL1SMN1; SMN2POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176310-B1 | Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents | UCB SA (GB) | 2007-02-13 | — | — | US | disclosed |