Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010491 | 0.78 | KMT2A (0.77) | KMT2AMEN1ALDH1A1KDM4ETSHR | |
| SCHEMBL791289 | 0.75 | MEN1 (0.71) | KMT2AMEN1MAPK1ALDH1A1KDM4E | |
| SCHEMBL5656394 | 0.74 | DRD4 (0.54) | ALDH1A1KDM4ETSHRHTTSMN1; SMN2 | |
| SCHEMBL5660210 | 0.72 | SMN1; SMN2 (0.55) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4004525 | 0.72 | HSD11B1 (0.60) | KMT2AMEN1ALDH1A1SMN1; SMN2DRD2 | |
| SCHEMBL29057493 | 0.72 | MEN1 (0.56) | KMT2AMEN1MAPK1ALDH1A1TSHR | |
| SCHEMBL29078376 | 0.71 | KMT2A (0.69) | KMT2AMEN1MAPK1ALDH1A1KDM4E | |
| SCHEMBL5605575 | 0.70 | MEN1 (0.63) | KMT2AMEN1MAPK1ALDH1A1TSHR | |
| SCHEMBL27008685 | 0.70 | OGA (0.76) | — | |
| SCHEMBL7542659 | 0.70 | ALDH1A1 (0.60) | KMT2AMEN1ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176310-B1 | Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents | UCB SA (GB) | 2007-02-13 | — | — | US | disclosed |