SCHEMBL5656903

SCHEMBL5656903

O=C(O)c1cc(=O)cc2oc3cc(O)ccc3cc1-2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
MIF P14174 9/20 0.51
NPC1 O15118 1/20 0.50
ESR2 Q92731 1/20 0.49
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
KDM4E B2RXH2 3/20 0.48
GLA P06280 3/20 0.48
GAA P10253 3/20 0.48
PTGS1 P23219 2/20 0.48
S1PR4 O95977 1/20 0.48
MAPT P10636 1/20 0.48
S1PR1 P21453 1/20 0.48
POLB P06746 2/20 0.47
ALPL P05186 1/20 0.47
ALPI P09923 1/20 0.47
ALPG P10696 1/20 0.47
ALDH1A1 P00352 3/20 0.47
HPGD P15428 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19633771 0.84 MIF (0.48) USP2L3MBTL1MIFNPC1ESR2
SCHEMBL37883 0.75 MAOA (0.76) MIFNPC1MEN1KMT2AKDM4E
SCHEMBL31500937 0.75 APP (0.57) USP2L3MBTL1ESR2MEN1KMT2A
SCHEMBL5656898 0.74 TYR (0.56) MIFNPC1ESR2MEN1KMT2A
SCHEMBL8764976 0.74 PTGS1 (0.58) MIFNPC1ESR2MEN1KMT2A
SCHEMBL20254033 0.71 USP2 (0.77) USP2L3MBTL1MEN1KMT2APOLB
SCHEMBL308343 0.71 SHBG (0.67) USP2MIFESR2MEN1KMT2A
SCHEMBL6407371 0.70 FLT3 (0.76) USP2MIFNPC1MEN1KMT2A
SCHEMBL14640188 0.70 USP2 (0.74) USP2L3MBTL1MEN1KMT2APOLB
SCHEMBL1437042 0.70 USP2 (0.78) USP2L3MBTL1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1161265-A4 METHOD FOR THE IDENTIFICATION AND REMOVAL OF NITS FROM HAIR REID LORI FOX (US) 2006-01-11 EP disclosed
EP-1161265-A1 METHOD FOR THE IDENTIFICATION AND REMOVAL OF NITS FROM HAIR Reid, Lori Fox (US) 2001-12-12 EP disclosed
WO-2000054816-A1 METHOD FOR THE IDENTIFICATION AND REMOVAL OF NITS FROM HAIR REID LORI FOX (US) 2000-09-21 WO disclosed